Pregnancy outcomes vary with disease progression in pregnant women with schizophrenia
Journal Title: Clinical and Experimental Obstetrics & Gynecology - Year 2019, Vol 46, Issue 2
Abstract
Purpose of investigation: It has been reported that pregnant women with schizophrenia have increased risk of adverse pregnancy outcomes. In this study, the authors aimed to investigate whether being admitted to the psychiatric ward during pregnancy affected pregnancy and neonatal outcomes in pregnant women with schizophrenia. Materials and Methods: One hundred and forty-eight women with schizophrenia who delivered after 22 gestational weeks at the present tertiary care center were classified into the inpatient group who needed to be admitted to the psychiatric ward because of aggravation of schizophrenia symptoms during pregnancy, and the outpatient group who did not require hospitalization. Patient characteristics, maternal outcomes, neonatal outcomes, and postpartum childcare environment were compared and analyzed. Results: There were no significant differences in the maternal outcomes between the inpatient and outpatient groups. The inpatient group had significantly higher rates of neonatal abstinence syndrome (13.8% vs. 0.8%, p = 0.001), placement in a child welfare facility (34.5% vs. 3.4%, p < 0.001), and intervention by hospital social workers (100% vs. 46.2%, p < 0.001) than the outpatient group. Conclusions: Maternal outcomes did not vary in pregnant women with schizophrenia regardless of disease conditions. Meanwhile, in mothers with poorly controlled disease condition, their neonates were at high risk of developing neonatal abstinence syndrome, and moreover, were more likely to need intervention by public authority such as social workers and child welfare facilities.
Authors and Affiliations
Eri Koga, Mio Takami, Yuichi Takahashi, Kazuo Seki, Fumiki Hirahara, Shigeru Aoki
Keywords
Related Articles
- EP ID EP620220
- DOI 10.12891/ceog4396.2019
- Views 77
- Downloads 0
Term pregnancy not requiring cerclage placement or tocolytic therapy in a patient with a unicornuate uterus and history of myomectomy
The authors present the case of a 28-year-old nulliparous woman, who successfully carried a term pregnancy in a unicornuate uterus with a solid non-communicating rudimentary horn, and a history of myomectomy, without cer...
Effects of selective agonists of adenosine, P2X, and P2Y receptors on motility of isolated fallopian tube
Background: During reproductive life of women, adenosine causes both contraction (with low concentrations) of fallopian tubes and inhibition of their spontaneous motor activity (with high concentrations). Objective: The...
Circulating vaspin and IL-6 concentrations in second trimester pregnancy with gestational diabetes
Objective: This study aims to compare serum vaspin and IL-6 concentrations between pregnant women with gestational diabetes mellitus (GDM) and normal glucose tolerance (NGT), as well as with non-pregnant healthy subjects...
Quantitative detection of cell-free fetal DNA in peripheral blood of pregnant women during early pregnancy
Objective: This study aimed for the quantitative detection of cell-free fetal DNA (cffDNA) in peripheral plasma of pregnant women, which provides basic data for clinical non-invasive prenatal screening in early pregnancy...
Fetal brain lactate peak measurement by magnetic resonance spectroscopy for prediction of fetal hypoxia in a case of unexplained third trimester recurrent fetal loses
Background: The fetal brain lactate level which is measured by magnetic resonance spectroscopy (MRS) is a compelling indicator for hypoxic/ischemic brain damage. Aim: The authors present a case of MRS diagnosed fetal bra...