PREPARATION AND EVALUATION OF COLON SPECIFIC IBUPROFEN TABLETS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 2
Abstract
The aim of the present study was done to evaluate drug release at the colon specific region by developing the formula which can deliver the drug at the colonic region of the GIT. For this particular study the pelletization process was adopted and the pellets which were formed were compressed into the tablets and the tablets which were formed were coated with Eudragit L100. The in vitro dissolution studies were carried out and test like hardness, friability and weight variation were carried out. In brief the formulation that was develop was the pH dependent one the widely used method for the developing the colon specific drug delivery.
Authors and Affiliations
Krunal Patel , Nabin Karna , Biswajit Biswal , Janki Patel
Keywords
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