Prescribing Pattern and Cost Analysis of β-Lactam Antibiotics in Rural Pediatric Patient: A Prospective Observational Study
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2017, Vol 6, Issue 4
Abstract
Beta-lactam antibiotics are the most widely used antibiotics used in the pediatric population; irrational prescribing of beta-lactam in the treatment process and its resistance in the pediatric population is the main concern of healthcare community. Objective: To assess the prescribing pattern of β- lactam antibiotic prescribed for treating a pediatric patient suffering from a commonly occurring infection. Methodology: The observational prospective study was conducted in 150 pediatric patients prescribed with beta-lactam antibiotics at MVJ medical hospital and research center for the period of six months (November2015–april2016). All required patient data are collected in specially designed case report form approved by pharmacy practice department; the data were analyzed using descriptive analysis. Result: 150 pediatric patients were assessed. The average number of drug per encounter was 4.51. The average number of beta-lactam per prescription was 1.02. Male account for 50.67%and female for 49.33% of the total case. LRTI 36.66%,enteric fever 18%,AGE 10.66% ,UTI 6.66%,meningitis 4%, tonsillitis 4%, diarrhea 2% were the most prevalent disease among pediatric and other constitute 18%. Cephalosporin group of antibiotic were most frequently prescribedi.e 77.14%, penicillin 22.86%, of which ceftriaxone 60.13%, cefotaxime 13.73%, cefpodoxime 3.26%, amoxicillin-clavulanic acid combination was 21.56%.Most beta-lactams were administered parenterally 88.89% and oral 11.11%.and 68% antibiotics were prescribed in generic name. Conclusion: Beta-lactam prescribing in pediatric patient is relatively high in rural part of Bangalore. Especially use of broad spectrum cephalosporin antibiotic result in bacterial resistance thus there is need for improving the prescribing pattern of antibiotic; thus development of guidelines for antibiotic prescription and use of an antibiotic for the appropriate disease can result in minimizing the adverse drug reaction with bacterial resistance in the pediatric patient.
Authors and Affiliations
Deepak Bhatt*| Pharm.D, Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore-560035, Ajay Shah| Pharm.D, Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore-560035, Dinesh K. yadav| Pharm.D, Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore-560035, Ajay K. Shah| Pharm.D, Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore-560035, Dr. NM Mahesh| M.Pharm, Ph.D. Professor and Head. Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore-560035, Dr. B. Ravichander| MD, Professor and Head, Department of Pediatrics, MVJ Medical College and Research Hospital, Bangalore-560029, Dr. Vidhya Alex| Pharm.D, Associate Professor, Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore-560035
Keywords
Related Articles
- EP ID EP4152
- DOI -
- Views 424
- Downloads 22
IN VITRO CYTOTOXICITY ASSESSMENT OF IMIQUIMOD LOADED SOLID LIPID NANOPARTICLES BASED GEL FORMULATION USING BASAL CELL CARCINOMA CELL LINE: PART-II
This study was undertaken to address the efficacy of newly formed Imiquimod loaded Solid Lipid Nanoparticles based gel formulation. The study evaluated the acute toxic effect of Solid Lipid Nanoparticles proposed for fu...
PHARMACOMETRIC BASED DESIGN AND ANALYSIS BRIDGING THE GAP FOR PEDIATRIC CLINICAL TRIALS
A major test is recognizing, enrolling, and enlisting patients. The accessible pool of kids for target implications is much littler than grown-ups, and moral stipulations essentially restrict the amount of participants.
UTILIZATION PATTERN AND MEDICATION ADHERENCE OF ORAL ANTI-DIABETIC MEDICATIONS AMONG TYPE 2 DIABETES MELLITUS PATIENTS IN RURAL AREAS OF KARNATAKA, SOUTH INDIA.
Objective: To assess the utilization pattern and medication Adherence of oral anti-diabetic medications among patients with type 2 diabetes mellitus in rural areas of Bangalore East. Methodology: A prospective observatio...
Effect of TonEBP on cardiovascular manifestations; influence of signaling mediators
Tonicity-responsive enhancer binding-protein (TonEBP or NFAT5), which belongs to the Rel/NFAT family of transcription factors, plays a critical role in the kidney by controlling the expression of osmoprotective genes i...
STUDY OF SAFETY AND EFFECTIVENESS OF SUBTENON’S ANESTHESIA VERSUS PERIBULBAR ANESTHESIA IN CATARACT SURGERIES.
Aim & Objectives of the study: To compare the safety and effectiveness of subtenon’s anesthesia verusus peribulbar anesthesia in small incision cataract surgeries done at Shri.B.M.Patil medical college hospital Bijapur....