Prevalence and Antifungal Susceptibilities of Candida spp from a South Indian Tertiary Care Hospital
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 2
Abstract
Introduction: Candida sp. is increasingly being implicated as the cause of both community acquired and Nosocomial infections. With development of new resistance patterns versus the inherent resistance present in some of the species isolated from critical care areas, the complications resulting from long term antibiotics, surgical and medical interventions and environmental colonization by the Candida sp. is becoming more prevalent. Method: Prevalence of different species and their antifungal susceptibilities grown from various samples received in 20 months were studied using semi-automated MiniAPI kits. Results of tests done on 356 isolates were collated and analysed retrospectively. Results: Of the 356 samples, C. tropicalis showed prevalence of 37.07% as compared to C.albicans 31.1%, C guilliermondii (11.8) and C parapsilosis (6.74%). Candida sp were found to sensitive to 5-Flucytocine and Amphotericin B. Resistance to Itraconazole was noted more than to Fluconazole. Conclusions: Infections with Candida spp are usually of low virulence and are associated with a few well-defined risk factors as immunocompromised state, Malignancy and steroid therapy. Understanding these risk factors, identifying the species with changing trends in antifungal resistance, instituting infection control practices to reduce morbidity and mortality in critical care areas can improve outcomes.
Authors and Affiliations
Swapna Kurup Rajgopal
Keywords
Related Articles
- EP ID EP265336
- DOI 10.17511/ijmrr. 2017.i02.01
- Views 163
- Downloads 0
Role of susceptibility weighted imaging in characterization of intracranial lesions
Background: Intrinsic differences between magnetic susceptibility of tissues can be used to generate a unique type of contrast in Magnetic Resonance Imaging (MRI), particularly to characterize tissues and improve the sen...
Diverse criteria’s-disparate prevalence rates: prevalence of metabolic syndrome by modified NCEP-ATP III and IDF criteria
Background: Metabolic syndrome is a cluster of metabolic risk factors including central obesity, glucose intolerance, atherogenic dyslipidemia and hypertension. Studies have shown a prevalence of 10 - 84% in general popu...
A study of functional outcomes of distal humerus fractures operated by triceps reflecting approach
Introduction: Approaches to distal humerus has been a great controversy of which cheverons osteotomy is considered a gold standard. However it is associated with implant and procedure related complication, Hence we studi...
Interstitial lung diseases - a tertiary care center experience
Introduction: Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with substantial morbidity and mortality and pose diagnostic and therapeutic challenges to the clinician. Diagnosis of...
A quadrupled semitendinosus only anterior cruciate ligament reconstruction with tibial suspensory fixation
Purpose: Study is designed to analyze the postoperative outcome of arthroscopic ACL reconstruction with quadrupled semitendinosus tendon autograft fixed in femoral tunnel using tight rope and in the tibial tunnel using s...