PREVALENCE OF THYROID CARCINOMA IN CLINICALLY DIAGNOSED MULTINODULAR GOITRE IN A TERTIARY CARE CENTRE- A RETROSPECTIVE DESCRIPTIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 53
Abstract
BACKGROUND Multinodular goitre is a very common, usually benign thyroid disorder, but sometimes occurrence of malignancy is reported as a histopathological surprise. Longstanding multinodular goitre has been suggested as a predisposing factor, since areas with iodine deficiency related endemic goitre have a high incidence of follicular carcinoma. In this study, we have evaluated the prevalence of incidental or occult carcinoma and thyroiditis in thyroidectomies performed for clinically benign multinodular goitres. We also attempted to find if a more radical approach is needed in the management of clinically benign multinodular goitres. In this study, we aimed to identify the prevalence of carcinoma and thyroiditis clinically and on fine needle aspiration cytologically looking benign multinodular goitres. This study also intended to identify the relation of Sex, Age and Duration of illness from thyroid carcinoma. MATERIALS AND METHODS This is a retrospective descriptive study of patients with clinically and ultrasonographically proved multinodular goitre treated in one year. Fine Needle Aspiration Cytology proved malignancy is excluded from the study population. All the thyroidectomy specimens were pathologically studied and correlated with clinical findings. RESULTS Out of 303 patients, 90.4% (274) were females and 9.6% (29) were males. 50.8% were below 40 years and 49.2% were above 40 years. Duration of illness is 1 - 20 years. 64.4% were pathologically Benign Multinodular goitre only. 8% was having malignancy along with Multinodular goitre, of which 7.3% was papillary carcinoma and 0.7% was Follicular carcinoma. CONCLUSION It is found that prevalence of carcinoma in clinically multinodular goitres is 8%, which was not detected by Fine Needle Aspiration Cytology. No correlation with duration of illness. Incidence of Papillary Carcinoma is more in clinically benign Multinodular goitres than Follicular Carcinoma against what is said in Western literature.
Authors and Affiliations
Premlal Ayyappan Prasanna, Rishikesan Nair Kavsthubham Venugopalan Nair, Resmi Madhusoodanan Santhakumar
Keywords
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- EP ID EP220257
- DOI 10.14260/Jemds/2017/864
- Views 98
- Downloads 0
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