Primary amenorrhoea – a single centre experience of 38 cases

Journal Title: Obs Gyne Review: Journal of Obstetric and Gynecology - Year 2015, Vol 1, Issue 1

Abstract

Introduction: Primary amenorrhoea is defined as absence of menstruation by the age of 14 in absence of secondary sexual characteristics & by age 16 regardless of the presence or absence of secondary sexual characteristics. It occurs in around 1-4% of women in reproductive age group. The common causes of primary amenorrhoea include outflow tract disorders or uterine abnormalities, ovarian disorders, pituitary dysfunction, and hypothalamic dysfunction.The data of primaryamenorrhoea from our country is limited due to poor reporting and frequent loss to follow up. Hence we undertook this prospective study to determine the etiology for primary amenorrhoeabased on clinical examination and laboratory investigations. Methodology: This prospective study was done in Gynecologic Clinic of Sunrise Hospital between August 2013 to May 2015. The work up of primary amenorrhoea patients comprised of 1) History taking 2) Physical examination 3) Laboratory investigations. Patients were classified into 5 groups based on the compartment of organs involved.I- End organ failure/ outflow tract obstruction, II- Gonadal failure, III- Pituitary cause, IVHypothalamic cause, V- Other causes. Results: In our study, the 2 most common etiologic factors of primary amenorrhoeawere mullerian agenesis (65.78%) and gonadal dysgenesis (21.05%).Hypogonadotrophichypogonadism was noted in 10.52% of cases. Range of average age of the patients when they first consulted the physician was 14 to 33 years. Conclusion: Prompt reporting and awareness of available treatment options based on the etiology can make a huge difference in this often underreported disorder.

Authors and Affiliations

Balampa P, Rabindran Rabindran, Pavani Pavani

Keywords

Related Articles

Primary amenorrhoea – a single centre experience of 38 cases

Introduction: Primary amenorrhoea is defined as absence of menstruation by the age of 14 in absence of secondary sexual characteristics & by age 16 regardless of the presence or absence of secondary sexual characteristic...

A study of efficacy of oral probiotics in management of cases with symptomatic white discharge per vagina in a tertiary care hospital

Background: Urogenital infections are the most common gynecological condition constituting about 25% of outpatients. Because of higher recurrence rates and resistance to standard antimicrobials now a days the use of prob...

Case report of primary serous adenocarcinoma of fallopian tube- a diagnostic dilemma

Historically, primary fallopian tube carcinoma constitutes 0.3% of all cancers of the female genital tract. But literature suggests that the primary fallopian tube carcinoma may be more common. The true incidence of fall...

Acute inversion of a nonpuerperal uterus-a rare case

Uterine inversion in a non-pregnant uterus is rare condition usually associated with uterine pathology. Its diagnosis is based on high index of suspicion. Surgery is the main modality of treatment with preferred route be...

A clinicopathological study of correlation of clinical, sonological and histopathological findings following hysterectomy for abnormal uterine bleeding based on PALM-COEIN Classification

Background: To identify the proportion of different causes of Abnormal Uterine Bleeding in women undergoing hysterectomy according to the PALM COEIN classification proposed by FIGO. Methods: Collection of data was done...

Download PDF file
  • EP ID EP331799
  • DOI 10.17511/jobg.2015.i1.02.
  • Views 184
  • Downloads 0

How To Cite

Balampa P, Rabindran Rabindran, Pavani Pavani (2015). Primary amenorrhoea – a single centre experience of 38 cases. Obs Gyne Review: Journal of Obstetric and Gynecology, 1(1), 9-13. https://www.europub.co.uk/articles/-A-331799