Primary Progressive Aphasia (A Case Report)
Journal Title: Journal of Neurological Sciences-Turkish - Year 2006, Vol 23, Issue 3
Abstract
Primary progressive aphasia (PPA), was first defined by Mesulam in 1982 as a ''slowly progressive language dysfunction without generalized dementia''. PPA is a neurodegenerative syndrome usually presented with anomia and reduced speech fluency, it is characterized by deterioration in language for least 2 years. Focal left perisylvian degeneration is thought to be responsible for this clinical syndrome. We present a 65 years old male patient, who presented with a progressive decline of language function, mainly in naming skills. Others mental functions were relatively preserved as well as an independence in the activity of daily livings. His cranial MRI imaging displayed a focal asymmetric left atrophy in the left anteriomedial temporal lobe. Asymmetrical hypoperfusion in the left parieto-temporal lobes were seen in his SPECT study. This case with clinical and radiological evidence of PPA is presented.
Authors and Affiliations
Gülbün YÜKSEL, Figen VARLIBAŞ, Geysu KARLIKAYA, Hülya TİRELİ
Keywords
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