Primary squamous cell carcinoma of breast: A Rare Case Report
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2017, Vol 3, Issue 2
Abstract
Primary squamous cell carcinoma (SCC) of breast is a pure epithelial type of metaplastic carcinoma accounting for less than 0.1% of all breast cancers. A 70 year female presented with left breast lump of 4 months duration. Toilet mastectomy was done. Histopathology proved it to be primary SCC (large cell keratinizing) of breast. On immunohistochemistry, tumor cells were positive for pancytokeratin and epidermal growth factor receptor and negative for estrogen, progesterone receptors and HER-2/neu (triple negative). On follow up, after 1 month, patient presented with recurrence and metastasis to ipsilateral axillary lymph nodes. This case is presented for its rarity.
Authors and Affiliations
Rekha M. Haravi, Bhumika J. Bhandari, Shreekant K. Kittur, Sabu N. Satihal
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