Process for Preparation of Vitamin C and Method for Determination of Vitamin C in Tablets
Journal Title: Surgery & Case Studies: Open Access Journal - Year 2018, Vol 1, Issue 3
Abstract
Procedure for calcium ascorbate (VITAMIN-C) includes such technological steps as reaction of ascorbic acid on calcium carbonate in water. In recent years, the determination of vitamin C has become an important subject in the field of biochemistry and commercial foods. This is because vitamin C plays an important role in maintaining human health. Due to the importance of vitamin C in human beings, the quantitative analysis of vitamin C has gained a significant increase in several areas of analytical chemistry such as pharmaceutical and food applications. There are numerous methods for the determination of vitamin C in a variety of natural samples, biological fluids and pharmaceutical formulations. The prepartaion method and methods for the determination of vitamin C are spectrophotometric methods and non-spectrophotometric methods (Arya and Mahajan, 1997). For non-spectrophotometric methods are such as high-performance liquid chromatography (HPLC), titration, enzymatic method and fluorometry (Arya, Mahajan and Jain, 2000). Direct spectrophotometry also has been applied to determine the vitamin C content in soft drinks, fruit juices, and cordials after correction for background absorption in the UV region. Ascorbic acid (vitamin C) is a water-soluble vitamin. It occurs as a white or slightly yellow crystal or powder with a slight acidic taste. It is an antiscorbutic product. On exposure to light, it gradually darkens. In the dry state, it is reasonably stable in air, but in solution it rapidly oxidizes. Ascorbic acid (vitamin c) is freely soluble in water; sparingly soluble in alcohol; insoluble in chloroform, in ether, and in benzene. The chemical name of ascorbic acid (vitamin c) is L-ascorbic acid (vitamin c). The empirical formula is C6H806, and the molecular weight is 176.13. The synthesis of ascorbic acid was achieved by Reichstein in 1933, followed by industrial production of ascorbic acid two years later by Roche. Today, vitamin C identical to that occurring in nature is produced on a very large industrial scale. The ultimate raw material for the production of vitamin C (ascorbic acid) is corn or wheat. This is converted via starch to glucose by specialist companies, and then to sorbitol. We produce the pure final products from sorbitol in a series of biotechnical, chemical processing and purification steps.
Authors and Affiliations
Krishnasarma pathy
Keywords
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- EP ID EP637706
- DOI 10.32474/SCSOAJ.2018.01.000114
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