Profile of Person Affected by Leprosy with Clinical Relapse among in High Endemic State of India
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2018, Vol 8, Issue 3
Abstract
Profile of Person Affected by Leprosy with Clinical Relapse among in High Endemic State of India Sunil Vilasrao Gitte1, Chaitanya Nigam1, Ashish B Chakraborty1, Krishnamurty Kamble1, Mukesh Soni1, Rupam Gahlot2 1Regional Leprosy Training and Research Institute, Lalpur, Raipur, Chhattisgarh, India 2Department of Microbiology, Government Medical College, Rajnandgaon, Chhattisgarh, India ABSTRACT Objective: Relapse is not an unusual phenomenon in leprosy, there are many predisposing factors which may lead to occurrence of relapse; some of these include the presence of persistent bacilli, drug monotherapy, inadequate or irregular therapy. Patients usually presents with presence of multiple skin lesions and/or thickened nerves, reason for early relapse is probably bacillary persistence due to inadequate treatment and for late relapse due to or re-infection. The objectives of this study are to assess various clinico-epidemiological factors associated with the occurrence of relapses in leprosy patients. Methods: A hospital record based retrospective follow-up study has been performed and 117 relapse cases of leprosy were included. Leprosy relapse cases presented in the study hospital were interviewed using a predesigned and pretested preformed. Each patient was subjected to clinical, bacteriological and disability assessments for diagnosis of relapse and followed until the completion of multi drug therapy. Results: During a study period, relapse was seen more in male as compared to female. The duration between cessation of the treatment and re-appearance of new lesions varied from 1 to 33 years. Disability proportion was high among MB patients. Conclusion: Relapse in leprosy should be thoroughly examined and looked for drug resistance. J Microbiol Infect Dis 2018; 8(3):103-107
Authors and Affiliations
Sunil Vilasrao Gitte, Chaitanya Nigam, Ashish B Chakraborty, Krishnamurty Kamble, Mukesh Soni, Rupam Gahlot
Keywords
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