Prognostic significance of total platelet count with PICU outcome
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2016, Vol 3, Issue 6
Abstract
Background: Platelets in addition to their contribution in hemostasis are inflammatory cells having important role in host defense and can be of prognostic significance. Aim: Present study aims to evaluate the relationship of platelet, leucocyte count and C– reactive protein with outcome of cases admitted to Pediatric Intensive Care Unit (PICU). Material and Method: A prospective cohort study of 84 patients admitted for at least 3 days in the PICU at Institute of Medical Sciences and SUM Hospital, Bhubaneswar, India was undertaken from August 2015 to February 2016. Patient data related to socio-demographic profile, patient history, clinical features and investigational findings were recorded. Results: The mean platelet count on day of admission was 6.13 lakhs/cumm which decreased during the stay and showed significant positive correlation with the duration of PICU stay and death outcome. The change in platelet count during stay also showed significant association with death outcome. Significant correlation was observed between total leucocyte count and C-reactive protein with duration of stay. Also duration of stay is significantly associated with the death outcome. Conclusion: Platelet, leucocyte and C- reactive protein status on day of admission significantly correlates with duration of stay and death as outcome. Decreased platelet count during stay necessitates thorough evaluation of cases.
Authors and Affiliations
Swarup Kumar Bisoi, Mamata Devi Mohanty
Keywords
Related Articles
- EP ID EP225042
- DOI 10.17511
- Views 162
- Downloads 0
Sonographic features of neonatal intestinal malrotation and volvulus
Background: Normally third portion of duodenum is always retromesenteric-retroperitoneal. Demonstration of intramesentric position of D3 on ultrasound can help in diagnosis of malrotation. Objective: The aim of this stud...
Can thyroid dysfunction in mothers influence neonatal thyroid profile?
Thyroid hormones play a critical role in normal CNS maturation. Fetus is entirely dependent on maternal thyroid hormone before the onset of endogenous thyroid hormone production. Maternal hypothyroidism alone during earl...
Problems with exclusive breast feeding– A study in state referral hospital at Falkawn, Mizoram, India
Background: Exclusive breastfeeding is the best way to feed children below the age of 6 months. However, there are problems that hinder exclusive breastfeeding. The aim of this study is to identify problems hindering exc...
Urinary lactate to creatinine ratio in neonates with perinatal asphyxia and its correlation with severity of hypoxic ischemic encephalopathy
Background: Neonates with perinatal asphyxia are prone to development of hypoxic ischemic-encephalopahty (HIE). There are no reliable methods for prediction of HIE in these neonates. Objectives: To determine urinary lact...
Relevance of lung ultrasound in diagnosis of severe neonatal pneumonia
Introduction: Neonatal pneumonia is a serious respiratory infection accounting for 10% of the neonatal deaths. Objective: The aim and objective of our study was to evaluate the accuracy of lung ultrasound to diagnose neo...