Progression of Buerger’s Disease in the Absence of Conventional Tobacco Exposure: A Case of Vape Associated Disease
Journal Title: Journal of Dermatology Research - Year 2025, Vol 6, Issue 2
Abstract
Thromboangiitis Obliterans (TAO), or Buerger’s disease, is a nonatherosclerotic, inflammatory vasculopathy primarily affecting small and medium-sized vessels, most often in the distal extremities and is strongly associated with tobacco use. We present the case of a 29-year-old male with minimal prior cigarette smoking history who developed clinically apparent Buerger’s disease only following exclusive and heavy use of e-cigarette vaping. While cigarette, tobacco smoke is a well-established trigger, it is unclear what role nicotine or e-cigarette vape antigens may play in the role of Buerger’s disease. This case supports growing evidence that nicotine delivery systems, including e-cigarettes, may contribute to the pathogenesis or progression of Buerger’s disease. Clinicians should be aware of vaping as a potential risk factor and counsel patients with Buerger’s disease on the importance of complete smoking cessation, regardless of delivery method.
Authors and Affiliations
Nashwah Memon1,3, Omar Alani2, S Minhaj Rahman3, Fahad Ahmed4, Adel Haque5,6*
Keywords
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- EP ID EP767515
- DOI https://doi.org/10.46889/JDR.2025.6205
- Views 14
- Downloads 0
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