Proliferative fibrocystic lesions in association with carcinoma breast- Study of mastectomy specimens
Journal Title: International Journal of Biomedical and Advance Research - Year 2015, Vol 6, Issue 8
Abstract
Background: Breast cancer remains a global health problem with an increasing incidence. Proliferative breast diseases are recognized as one of the risk factors in the development of carcinoma. The study was undertaken to know the frequency of proliferative fibrocystic lesions in association with breast carcinomas in mastectomy specimens. Material and methods: The present study included 100 cases of mastectomies for carcinoma breast at Kempegowda Institute of Medical Sciences, Bangalore from August 2010 to July 2013. The tumor and the surrounding breast tissue were studied grossly and microscopically for any co-existing neoplastic and non neoplastic lesions like epithelial hyperplasia, cystic change, apocrine metaplasia, fibrosis and adenosis. Results: The study included 100 cases of breast carcinomas. The predominant type of carcinoma (85%) was infiltrating ductal carcinoma-no specific type. Proliferative breast lesions were noted in 38 cases (38%), nonproliferative breast lesions in 27 cases (27%) and there were no changes in 35 cases (35%). Of 38 cases, proliferative lesions with atypia were noted in 20 cases and proliferative lesions without atypia were noted in 18 cases. Conclusion: Proliferative lesions in the breast carry an increased risk of developing malignancies especially when there is atypia. Women, who have been diagnosed as having proliferative breast disease, require careful follow-up, with annual mammographic screening being mandatory for women with atypical hyperplasia
Authors and Affiliations
Shashikala R, Savithri Ravindra
Keywords
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- EP ID EP344072
- DOI 10.7439/ijbar.v6i8.2321
- Views 93
- Downloads 0
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