Prospective study on cord bilirubin level as a predictor of Hyperbilirubinemia in term healthy neonates
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2017, Vol 4, Issue 9
Abstract
Introduction:Neonatal jaundice or hyperbilirubinemia is a cause of concern for parents and pediatricians, with more than 60% being affected by this condition in the first few weeks. Prediction of high risk neonates for hyperbilirubinemia will help in developing appropriate follow-up programs for managing the condition. It will also help in reducing duration of hospital stay for low-risk neonates. Objective: To estimate the predictive value of umbilical cord blood bilirubin level for the development of significant hyperbilirubinemia in healthy, full term neonates.Methodology:A prospective study on 450 healthy full tem newborns was undertaken in the postnatal care ward of a tertiary level teaching hospital. The study focused on predictive ability of cord blood bilirubin levels and subsequent development of hyperbilirubinemia.Results:Clinically significant hyperbilirubinemia was detected in 254 out of 450 newborns (56%) neonates. Majority of participants had cord blood bilirubin levels ranging from 1.5-2.4mg/dl. Only 1.3% (3 neonates) had levels ≥3 mg/dl. Majority of newborns in our study (60%) had an intermediate risk of developing hyperbilirubinemia, and only 1.3% (31) belonged to the high risk category on stratifying risks. Cord bilirubin cut off value of 1.9 mg/dl predicted subsequent hyperbilirubinemia with sensitivity of 91.8% and specificity of 52.4%. Conclusion:Study highlights that risk stratification is an excellent method of tracking newborns with hyperbilirubinemia as newborns with hour-specific bilirubin value in low risk zone have reduced risk of developing subsequent significant hyperbilirubinemia. The probability of developing this condition in neonates was not significantly different in males and females.
Authors and Affiliations
Bindu A, Shinoj Shinoj, P. M. Kutty
Keywords
Related Articles
- EP ID EP285887
- DOI 10.17511/ijpr.2017.09.03
- Views 170
- Downloads 0
Predictors of Hypoxemia in children (2-60 months) with lower respiratory tract infection
Introduction: Acute lower respiratory tract infection specifically pneumonia, account for considerable number of deaths in under 5 children in our country. Hypoxemia is a dangerous sign which needs to be promptly treated...
High flow nasal cannula vs non-invasive ventilation in pediatric ARDS: an RCT
Introduction: Pediatric Acute Respiratory Distress syndrome (PARDS) has been re-defined (2015) as per the final recommendations of the Pediatric Acute Lung Injury Consensus Conference. The use of high flow nasal cannula...
Psychiatric morbidity in school going children of Bikaner
Background: Psychiatry morbidity is a reality in our present day society. Its measurement requires a proper, standardized, screening tool and an extensively researched classification of psychiatric ailments. This study a...
3 days vs. 7 days course of intravenous antibiotics for probable neonatal sepsis
Introduction: Duration of appropriate antibiotic therapy for neonatal sepsis does not have evidence-based guidelines. The rationale and safety of these recommendations have never been scientifically evaluated. Such untes...
Clinico-demographic Profile and outcome of acute poisoning among children- a single Centre observational study
Background: Poisoning in children is a global problem and no part of the world is exempt from this calamity. It is one of the commonest preventable emergencies encountered in pediatric practice. Methods: This prospectiv...