RAISED SERUM LDL IN CHRONIC EXCESS ALCOHOLISM AS A RISK FACTOR FOR STROKE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 13
Abstract
BACKGROUND As far as ischaemic stroke is concerned, prevention is only facilitated by an understanding of predisposing host, risk and environmental factors. WHO defines stroke as rapidly developed clinical signs of focal or global disturbance of cerebral functions lasting more than 24 hours or leading to death with no apparent cause other than vascular origin. The 24 hours “definition” excludes transient ischaemic attack (TIA). Cerebral thrombosis is usually the most frequent form of stroke encountered in clinical studies followed by haemorrhage. We wanted to analyse serum LDL, AST and ALT concentration in chronic excess alcoholism with stroke and to study the relation between LDL and stroke. METHODS This is a comparative cross-sectional study. The study population consists of two groups; group one consists of 50 persons with self-reported, regular, excess, chronic alcohol intake (greater than 400 g per week which approximately equal to 1400 ml per week or 200 ml per day); group two consists of patients with stroke who take alcohol similarly. Serum LDL was analysed, and statistical analysis made in relation to both the groups. RESULTS The mean values of serum LDL were significantly elevated in cases compared to controls with a p value at 0.021. CONCLUSIONS LDL which is the biological marker of atherosclerosis can be used to assess the risk of stroke especially in chronic excess alcoholism. Excessive drinking of alcohol with increased LDL-cholesterol compounds the risk for stroke.
Authors and Affiliations
Chelladurai Kandaswamy, Panimathi Rengaramanujam
Keywords
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- EP ID EP555764
- DOI 10.14260/jemds/2019/229
- Views 91
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