Randomized controlled study on comparative evaluation of 0.75% ropivacaine with 0.75% ropivacaine with dexmedetomidine in epidural anaesthesia in lower limb orthopaedic surgeries
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 7, Issue 3
Abstract
Background: Regional anesthesia and analgesia has the potential to provide excellent operating conditions and prolongedpost operative pain relief. Epidural blockade is becoming one of the most useful and versatile procedures in modern anesthesiology. It is more versatile than spinal anesthesia. It can be used to supplement general anesthesia. It provides better postoperative pain control and more rapid recovery from surgery. Aim: To study the time of onset of action of ropivacaine0.75% and ropivacaine0.75% with Dexmedetomidine when administered epidurally. Materials and Methods: The prospective, randomized, comparative study was conducted on 60 patients aged between 18-55 years posted for lower limbsurgeries. Study compared the potentiating effects of epidurally administerd dexmedetomidine when combined with Ropivacaine in terms of haemodynamic changes, onset of sensory and motor blockade, duration of analgesia, intra-operative haemodynamic changes and complications/adverse effects. Results: There was no significant difference in age, weight and height between the two groups. The early onset of sensory analgesia to T10 level and early onset of motor blockade in Group RD is statistically significant pvalue<0.05 (p value<0.0001).The time taken to reach the maximum level of sensory analgesia in Group RD was statistically significant p value<0.05(p value<0.0001). The delayed recovery of motor blockade in Group RD was statistically significant p value<0.05 (p value <0.0001).Duration of analgesia is prolonged in Group RD which is statistically significant p value<0.05 (p value<0.0001).There was no statistically significant difference in the pulserate, systolic blood pressure and diastolic blood pressure between the two groups. Conclusion: when dexmedetomidine 1mcg/kg added as adjuvant to 0.75% Ropivacaine in epidural anaesthesia in lower limb orthopaedic surgeries resulted in earlier onset of sensory analgesia to T10 level and helped in achieving the complete sensory anaesthetic level in a shorter period as compared to ropivacaine.
Authors and Affiliations
Sridevi 1, Patnana Pradeep Kumar
Keywords
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