Rationale of Parenteral Iron Sucrose Therapy in Gynecology Patients Awaiting Surgery: A Prospective Study from Central India

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Rationale of Parenteral Iron Sucrose Therapy in Gynecology Patients Awaiting Surgery: A Prospective Study from Central India

Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3

Abstract

Background: Iron deficiency anemia (IDA) is more prevalent in South Asian countries which accounts for more than half of the maternal death. India is the leader in maternal death due to IDA. Aims and Objectives: To study improvement in hematological parameters after parenteral Iron sucrose therapy in women undergoing major gynecological surgery. Materials and Methods: Thirty patients with iron deficiency anemia who were admitted for major gynecological surgery having hemoglobin <10 gm% were studied. Study cohort received 300 to 600 mg of iron sucrose by intravenous route. Hematocrit, mean corpuscular volume and haemoglobin were recorded before and after therapy at the end of one week. All the data were analyzed using IBM SPSS- ver.20 software. P values <0.05 was considered to be significant. Results: Most of the patients had age >40 years (66.7%), parity >2 (60%), education till 12th or below (100%) and had monthly income of 2000 or less (60%). Out of 30 patients, 53.3% received iron sucrose whereas 46.75% received iron sucrose with blood transfusion. In 26.7% patients hemoglobin was raised by 0.5 to 1 gm%, in 80% subjects MCV changed up to 10 fL and in 73% of the subjects haematocrit value changed by 5% or more. Conclusion: Treatment with parenteral iron sucrose with or without blood transfusion is effective in improving hemoglobin concentration in subjects with major gynecological surgery

Authors and Affiliations

Dr Sujata Bhargava

Keywords

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