Recent advances in antibody-drug conjugates for the treatment of gastric cancer
Journal Title: Biomedical Transformation - Year 2022, Vol 3, Issue 1
Abstract
Antibody-drug conjugates (ADCs), generally consisting of cytotoxic agents conjugated to monoclonal antibodies via linkers, are a new class of targeted antitumor therapeutics that combine the advantages of high specificity of antibody and high cytotoxicity of chemotherapy drugs. After decades of preclinical and clinical research, a group of ADCs have been widely used for treatments of many types of tumors. This review summarizes recent advances in ADCs for the treatment of gastric cancer.
Authors and Affiliations
Xiao Lihai, Xia Gang, Wang Jiancheng
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