Reference Value of Neutrophil-Lymphocyte Ratio in Healthy Sudanese in Khartoum
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 5
Abstract
Abstract: Neutrophil-lymphocyte ratio (NLR) has been recently identified as clinically useful predictive and prognostic biomarker in patients with the different medical illness. To assure easy application and interpretation, the reference value of such parameter should be established.To establish the Sudanese reference value for NLR; a total of 300 Sudanese healthy subjects(150 males, 150 females) with the different age groups between 5 and 85 (mean: 39 year)- were enrolled. A venous blood sample was collected from each subject and analyzed using a Sysmex-KX-21 automated blood analyzer. The NLR was calculated from the absolute number of neutrophils and lymphocytes. Reference value was calculated as mean-2SD to mean+2SD. Simple T-test was used to compare the reference value of WBCs count, neutrophils, lymphocytes, and NLR between both genders and different age groups.The following reference values were obtained for NLR – males 0.5-1.7, females 0.2-2.2; the overall reference value was 0.3-2.9. The mean of NLR in different age groups were as follow: 0.8, 1.3, 1.4, 0.9, 1.2, 1.2 in the age group of ˂20, 20-29, 30-39, 40-49, 50-59, ˃60 years old; respectively. There were no significant differences between males/females and individuals below/over 40 years old age, p-values were 0.1, 0.46 respectively. This study illustrated the importance of determining local reference value, because ethnic groups and instruments may vary from published reference values. The reference values for NLR do not vary with age or gender. This reference values pave the way for the clinicians to apply such parameter in the investigations of disease states. Keywords:Reference, value, Neutrophil, lymphocyte, ratio, Sudan
Authors and Affiliations
Marwa M. Mohamed, Nora M. Mahgoub, Nada M. Osman, Sahar S. Saeed, Thuwaiba Y. Elmubark, Awad-Elkareem Abass
Keywords
Related Articles
- EP ID EP372677
- DOI -
- Views 91
- Downloads 0
Awareness of the Practice and Uses of Contact Lens amongst Students in a Nigerian Tertiary Institution
Abstract:To assess the level of awareness and use of contact lens among tertiary students and to evaluate lens care practices among contact lens users.A descriptive cross sectional study was conducted among students in t...
Refractory hypokalemia as initial manifestation of Cushing’s syndrome complicating pregnancy
A pregnancy complicated by Cushing’s syndrome is a high-risk obstetric condition. The overlap in clinical features with pregnancy, as well as its rare occurrence, makes the diagnosis of Cushing’s syndrome difficult and o...
Chronic Pyogenic Osteomyelitis of the Rib: A Case Report in a Paediatric Patient
Rib osteomyelitis is extremely rare and accounts for less than 1% of haematogenous osteomyelitis. We report a rare case of pyogenic osteomyelitis involving the rib in a 5 year old male child who presented with a discharg...
Impact of Thyroid Dysfunction on Renal Glomerular Filtration Rate, Sodium and Potassium among Sudanese Patients Attending Ribat Teaching Hospital
Abstract: Thyroid hormones (TH) are essential for an adequate growth and development of the kidney. Thyroid dysfunction causes remarkable changes in glomerular, tubular functions, electrolyte and water homeostasis. The a...
Pregabalin Intoxication in a Patient with Heroin Addiction
Abstract: Pregabalin is an anticonvulsant which is an analog of gamma-aminobutiric. It increases normal GABA levels by binding to α2-δ subunit in voltage sensitive calcium channels and inhibiting excitator neuro-transmit...