Relation of neutrophil/lymphocyte ratio to resistant hypertension
Journal Title: The European Research Journal - Year 2016, Vol 2, Issue 3
Abstract
Objectives. Resistant hypertension has unfavourable effects on cardiovascular and other systems. The aim of this study was to investigate the association of neutrophil/lymphocyte (N/L) ratio and resistant hypertension. Methods. A total of 140 patients were included in the study. Ambulatory 24-hour blood pressure monitoring, transthoracic echocardiography and blood sample analyzing were performed in all patients. There were 60 patients with resistant hypertension group (mean age=55.1±9.7 years) and 80 patients with non-resistant hypertension group (mean age=56.8±14.1 years). Results. Mean neutrophil levels were significantly higher in resistant hypertension group (71.7±6.1% vs. 65.9±5.4%, p<0.001), while lymphocyte levels were significantly higher in non-resistant hypertension group (22±4.7% vs. 17.5±4.1%, p<0.001). N/L ratio was significantly higher in resistant hypertension group (4.3±1.2 vs. 3.1±0.9, p<0.001). In multivariate analysis, diabetes mellitus (odds ratio [OR]=2.857; 95% confidence interval [CI], 1.349-6.053; p=0.006), N/L ratio (OR=2.699; 95% CI, 1.821-4.002; p<0.001) and obesity (OR=3.429; 95% CI, 1.675-7.019; p=0.001) were independent predictors of resistant hypertension. Conclusion. The N/L ratio, which is cheaply and easily measurable laboratory data, is independently associated with resistant hypertension.
Authors and Affiliations
Necati Dagli, Orhan Dogdu, Omer Senarslan, Hasan Yucel, Hakki Kaya, Mahmut Akpek, Semih Eriten
Keywords
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- EP ID EP195333
- DOI 10.18621/eurj.2016.5000185856
- Views 108
- Downloads 0
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