Relationship of Gender and Serum Calcium and/or Phosphorus Levels on Admission with the Etiology and Early Prognosis of Hypercalcemia

Journal Title: The Medical Bulletin of Haseki - Year 2020, Vol 58, Issue 5

Abstract

Aim: Hypercalcemia (HCM) is a common clinical problem characterized by a serum corrected calcium (cCa) level of >10.7 mg/dL. Primary hyperparathyroidism and malignancy are mostly (90%) involved in the etiology. In this study, we aimed to determine the relationship of cCa and phosphorus (P) levels, cCa/P ratio and gender with the etiology of HCM and one-week mortality. Methods: Records of HCM patients older than 18 years of age who were hospitalized between January 1, 2017 and December 31, 2018 were retrospectively reviewed. Age, gender, cCa and P levels, HCM etiology and one-week survival status of the patients were recorded. Subsequently, the patients were divided into two groups according to whether the etiology of HCM was benign or malignant. Then, the groups were compared statistically in terms of gender, biochemical values and one-week survival. Results: The median level of serum cCa was found to be significantly higher in males (p<0.00). The frequency of malignancy-associated HCM was higher in males than in females. When the groups were compared, serum cCa and P levels were found to be higher in malignancy-associated group (p<0.000 and p=0.005, respectively). The one-week mortality rate in all patients was 18.99%. However, surprisingly, the one-week mortality rate in malignancy-associated HCM was lower than in the other group. Conclusion: Our study results show that serum cCa and P levels at the time of admission, and gender may help early evaluation of the etiology and/or prognosis of HCM.

Authors and Affiliations

Betül Erişmiş, Faruk Karandere, Deniz Yılmaz, Mehmet Hurşitoğlu, Abdulbaki Kumbasar

Keywords

Related Articles

Gliosarcoma Transforming from Giant Cell Glioblastoma: A Case Report and Review of the Literature

Giant cell glioblastoma and gliosarcoma are rare histological variants of glioblastoma multiforme. These are WHO Grade IV astrocytic tumors. While giant cell glioblastoma can be seen at younger age, gliosarcoma typically...

The Importance of Electromyographic Findings in Determining the Etiology of Mastalgia

Aim: The etiology of mastalgia is not fully understood. We evaluated the relationship between electromyography (EMG) measurements of the pectoralis major (PM) muscle and mastalgia in patients with non-cyclic unilateral m...

Can We Use the RIPASA Scoring System in Cases of Suspicious Acute Appendicitis?

Aim: Acute appendicitis is the most common cause of acute abdomen. Although the Alvarado scoring system is one of the most commonly used tools in the diagnosis of acute appendicitis, the Raja Isteri Pengiran Anak Saleha...

Comparison of Retrograde Intrarenal Surgery and Micro-percutaneous Nephrolithotomy for Kidney Stones 5-10 mm in Diameter

Aim: To compare the results of micro-percutaneous nephrolithotomy (micro-PNL) and retrograde intrarenal surgery (RIRS) for symptomatic renal stones 5-10 mm in diameter. Methods: A total of 86 patients, who underwent RIR...

Comparison of Complicatıons Following Laparoscopic Radical and Simple Nephreoctomy Using the Claviendindo Clasification

Aim: In this article, we aimed to compare the complications occurring after laparoscopic radical (LRN) and simple nephrectomy (LSN). Methods: After obtaining local ethics committee approval, we analyzed the records of a...

Download PDF file
  • EP ID EP691520
  • DOI 10.4274/haseki.galenos.2020.6161
  • Views 113
  • Downloads 0

How To Cite

Betül Erişmiş, Faruk Karandere, Deniz Yılmaz, Mehmet Hurşitoğlu, Abdulbaki Kumbasar (2020). Relationship of Gender and Serum Calcium and/or Phosphorus Levels on Admission with the Etiology and Early Prognosis of Hypercalcemia. The Medical Bulletin of Haseki, 58(5), -. https://www.europub.co.uk/articles/-A-691520