Relationship of Gender and Serum Calcium and/or Phosphorus Levels on Admission with the Etiology and Early Prognosis of Hypercalcemia
Journal Title: The Medical Bulletin of Haseki - Year 2020, Vol 58, Issue 5
Abstract
Aim: Hypercalcemia (HCM) is a common clinical problem characterized by a serum corrected calcium (cCa) level of >10.7 mg/dL. Primary hyperparathyroidism and malignancy are mostly (90%) involved in the etiology. In this study, we aimed to determine the relationship of cCa and phosphorus (P) levels, cCa/P ratio and gender with the etiology of HCM and one-week mortality. Methods: Records of HCM patients older than 18 years of age who were hospitalized between January 1, 2017 and December 31, 2018 were retrospectively reviewed. Age, gender, cCa and P levels, HCM etiology and one-week survival status of the patients were recorded. Subsequently, the patients were divided into two groups according to whether the etiology of HCM was benign or malignant. Then, the groups were compared statistically in terms of gender, biochemical values and one-week survival. Results: The median level of serum cCa was found to be significantly higher in males (p<0.00). The frequency of malignancy-associated HCM was higher in males than in females. When the groups were compared, serum cCa and P levels were found to be higher in malignancy-associated group (p<0.000 and p=0.005, respectively). The one-week mortality rate in all patients was 18.99%. However, surprisingly, the one-week mortality rate in malignancy-associated HCM was lower than in the other group. Conclusion: Our study results show that serum cCa and P levels at the time of admission, and gender may help early evaluation of the etiology and/or prognosis of HCM.
Authors and Affiliations
Betül Erişmiş, Faruk Karandere, Deniz Yılmaz, Mehmet Hurşitoğlu, Abdulbaki Kumbasar
Association Between Cardiothoracic Ratio and Mortality in Neonates with Pneumothorax
Aim: The aim of this study was to determine the effect of a reduction in the cardiothoracic ratio (CTR) on mortality in newborns with pneumothorax. Methods: Newborns with pneumothorax, who were admitted to our neonatal...
Efficacy of Presepsin as a Biomarker of Sepsis and Its Prognostic Value for Prediction of Mortality
Aim: We aimed to determine the efficacy of presepsin (PRE) as a biomarker of sepsis and to asssess its prognostic value for prediction of mortality were determined. Methods: Selected clinical data of 21 patients admitte...
Factors Affecting Recurrence-free Survival in Gastric Gastrointestinal Stromal Tumors: A Single Center Experience
Aim: Gastrointestinal stromal tumors (GISTs) are extremely rare. In this study, we aimed to analyze the factors affecting disease-free survival (DFS) in patients operated for non-metastatic gastric GIST (gGIST). Methods...
Analysis of Childhood Mortality in Emergency Department
Aim: The aim of the present study was to analyze the mortality rate, demographic characteristics and cause of death in pediatric patients who were referred to our emergency department. Methods: Patients aged 0-18 years...
Evaluation of Quality of Life and Anxiety Disorder in Children and Adolescents with Primary Headache
Aim: To investigate the effect of coexistence of primary headache with depression, anxiety, and anxiety disorder on patients’ quality of life and the variability of this effect according to the types of primary headache...