Renal Protective effects of Melatonin in rat treat by Gemcitabine
Journal Title: International Journal of Veterinary Science and Research - Year 2017, Vol 3, Issue 2
Abstract
Nephrotoxic side effects of gemcitabine have been reported in patients receiving this drug medication. Melatonin is a potent free radical scavenger and antioxidant and has protective effects against ischemic damage. In the present study, we examined the relationship between the renal protective effects of melatonin in tubular damage induced by gemcitabine. This study was conducted simultaneously as a case of 48 male wistar rat, weighing approximately 20 ± 250 g and aged 8 weeks were used. The rats were randomly divided into 3 groups.
Authors and Affiliations
Mortazavi Pejman, Ahmadnezhad Behnam, Pousty Iraj, Panahi Negar, Aghazadeh Mitra, Shalikar Mostafa, Ramezani Vahid, Meybodi Maryam Aghaie
Keywords
Related Articles
- EP ID EP554168
- DOI 10.17352/ijvsr.000025
- Views 55
- Downloads 0
Largemouth Bass Pond Culture in China: A Review
Largemouth bass micropterus salmoides natives to freshwater area of North America, which is a kind of famous global economic fish, and belongs to Centrarchidae, Perciformes in taxonomy. The fish has been extensively cult...
Review on Practical Guidance of Veterinary Clinical Diagnostic Approach
Animal disease problems have been investigated by veterinarians through undertaking a careful and clinical examination with the objective of recognizing the nature of the affection. So, that effective treatment and contr...
Current Status of Grevy Zebra: A Review
Grevy’s zebra is a member of the horse family Equidae and so is closely related to horses, asses and other zebras. They inhabit dry desert regions and open grasslands. Grevy’s zebra is one of the world’s most threatened...
Mesenchymal stem cells from the domestic ungulates: trends and outliers
Mesenchymal stem cells (MSCs) are a valuable source for regenerative therapy and tissue engineering. MSCs are multipotent adherent stem cells that can be isolated from different adult and fetal tissues. In contrast to hu...
Study on Effect of Diatomaceous Earth (DAE) on Aflatoxin-Induced DNA Damage in Visceral and Lymphoid Organs in Broiler Chicken
Background: Limited information exists concerning on the effect of diatomaceous earth (DAE) on aflatoxin-induced DNA damage in visceral and lymphoid organs. Objectives: The present investigation is an attempt to detect...