Research progress in sensitivity to inhalation anesthetics
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 4
Abstract
Inhalation anesthetics have both sedative, analgesic and muscle relaxing effects,and are widely used in clinical practice. Hypersensitivity to inhalation anesthetics predicts poor postoperative outcomes. Current studies have shown that some genetic mutations, ion channels or receptors, changes in metabolites, mitochondrial function are associated with the sensitivity of human or experimental animals to inhalation anesthetics. Therefore, this paper will briefly review the research progress in the mechanism of inhalation anesthetics sensitivity from gene mutation, ion channels or receptors, metabolites, and mitochondrial function.
Authors and Affiliations
REN Qiyang, WEI Yiyong, WANG Haiying
Effect of esketamine combined with serratus anterior plane block on postoperative analgesia after modified radical mastectomy for breast cancer
Objective To explore the effects of esketamine combined with serratus anterior plane block (SAPB) on postoperative analgesia, anxiety and depression in patients with breast cancer undergoing modified radical mastectomy....
Comparison of the efficacy and safety of programmed cell death protein 1 inhibitors combined with albumin-paclitaxel with or without platinum in the treatment of advanced metastasis or recurrent cervical cancer
<b>Objective</b> To compare the efficacy and safety of programmed cell death protein 1 (PD-1) inhibitor + albumin paclitaxel and platinum + PD-1 inhibitor + albumin-paclitaxel in the treatment of advanced metastasis or r...
Research progress on denervation in cardiovascular diseases
Denervation is closely related to many cardiovascular diseases, such as myocardial infarction, myocardial ischemia-reperfusion injury, hypertension, arrhythmia, heart failure, atherosclerosis and ventricular remodeling....
Trans-segmental shunt surgery for the treatment of syringomeylia resulting from trauma and infection
<b>Objective</b> To investigate the clinical effect of transsegmental shunt surgery in the treatment of syringomyelia due to trauma and infection in perspective of cerebrospinal fluid dynamics.<b>Methods</b> A total o...
Expression and significance of Toll-like receptor 5 in peripheral blood mononuclear cells of patients with rheumatoid arthritis
Objective To examine the expression levels of Toll-like receptor 5 (TLR5) on peripheral blood monocytes in patients with rheumatoid arthritis (RA), and to explore its clinical significance. Methods A total of 140 RA pat...