Research progress of extracellular vesicles in the theranostics of kidney diseases
Journal Title: Biomedical Transformation - Year 2022, Vol 3, Issue 2
Abstract
Extracellular vesicles (EVs) are lipid bilayer-enclosed structures released by cells and encapsulate bioactive cargoes that act as an emerging messenger of intercellular communication in the development of kidney diseases. Currently, an increasing number of studies documented that, urinary EVs are packed with proteins and RNAs derived from renal resident cells, which could be served as a source of diagnostic biomarker. Furthermore, EVs are natural nanocarriers in the body with intrinsic characteristics, including great biocompatibility, low immunogenicity and low toxicity， which makes them great potential to apply for the treatment of kidney diseases. This review will focus on the current studies on EVs-based theranostics of kidney diseases.
Authors and Affiliations
Zhang Yilin, Tang Taotao, Liu Bicheng
Keywords
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- EP ID EP766829
- DOI 10.12287/j.issn.2096-8965.20220205
- Views 17
- Downloads 0
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