Research progress of fibroblast growth factor receptor in gastric cancer
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 2
Abstract
The incidence and mortality of gastric cancer are in the forefront of the tumor, and the prognosis is poor, especially in the middle and advanced stage. Even with comprehensive treatment, the 5- year survival is very low. The development of precision medicine has extended the survival of patients, and fibroblast growth factor receptor (FGFR) has gradually become a popular target for the treatment of gastric cancer. In this paper, the common FGFR alteration types in gastric cancer and the exploration of FGFR inhibitors in the field of gastric cancer were reviewed, and the challenges were analyzed.
Authors and Affiliations
CHEN Meili, YUAN Yihang, YANG Hui, RUAN Luxi, LEI Jing, ZHANG Quan'an
Keywords
Related Articles
- EP ID EP736510
- DOI 10. 13429/j.cnki.cjcr.2024.02.006
- Views 42
- Downloads 0
Advances in CT-based artificial intelligence techniques for lung nodule diagnosis
Lung cancer is one of the common malignancies worldwide. Lung nodules, defined as early stage manifestations, are critical for early detection and diagnosis to reduce mortality. In recent years, CT based artificial intel...
Research advances on the association of nicotinic acetylcholine receptor-related genes and their polymorphisms with lung cancer
Pulmonary embolism and deep venous thrombosis are collectively referred to as venous thromboembolism, while pulmonary embolism is generally caused by deep venous thrombosis, which has the characteristics of sudden and mo...
Dynamic evolution process of tumor microenvironment in colorectal cancer metastasis
"In the process of colorectal cancer metastasis, the tumor microenvironment interacts with primary tumors, secondary tumors, circulating tumor cells, and disseminated tumor cells. This article introduces its dynamic evol...
Evaluation of methylene blue combined with 99mTc-sulfur colloid in sentinel lymph node biopsy of breast cancer for lymph node metastasis
Objective To investigate the application of <99mTc-sulfur colloid (<sup>99m</sup>Tc-SC) lymph node imaging with methylene blue tracing during sentinel lymph node biopsy (SLNB) procedures and its importance in evaluatin...
Clinical effect of Qingxiao Formula combined with silk seton therapy by applying Badu Shengji Powder on areola fistula of non-lactating mastitis with liver meridian stagnation heat syndrome
Objective：To observe the clinical effect of Qingxiao Formula combined with silk seton therapy by applying Badu Shengji Powder on areola fistula of non-lactating mastitis with liver meridian stagnation heat syndrome. Met...