Resveratrol-based Nutraceuticals for the Management of Diabetes and Obesity: Real Therapeutic Potential or a mere Palliative?
Journal Title: Archives of Diabetes & Obesity - Year 2018, Vol 1, Issue 2
Abstract
It is well known that obesity and diabetes (more specifically, the type 2 diabetes mellitus, T2DM) are currently a growing public health problem, which involves several millions subjects in the World. Years ago, indeed, the term “diabesity” was coined highlighting not only the strong pathogenic relationship between obesity and T2DM, but also the pandemic aspect that link these two diseases. The increasing global prevalence of diabesity represents a grave concern in terms of public health and, at the same time, medical costs, resulting in a serious social economic issue. Periodically, several scientific societies elaborate guidelines for the management of obesity and T2DM, mainly based on a particular interest in life-style and nutrition, as a useful strategy for prevention and treatment. In addition to the life-style intervention, a large number of drugs are currently available, and some of them (e.g. metformin or incretine-mimetic) are used both in case of diabetes and/or obesity. These pharmacological treatments, however, are not without side-effects. For this reason, the interest in natural drugs is nowadays emerging. Beside the well-known phytotherapy, based on the use of medical herbs with documented beneficial effects on human health, a consolidated and growing interest is currently in nutraceutical. This term is a crasis between the words “nutrition” and “pharmaceutical”, coined in the 1989 by Dr. S. DeFelice. Nutraceutical, thus, is the science studying chemical, composition and medical effects of the food- or animal-derived bioactive compounds, underling the strong influence of the diet on health.
Authors and Affiliations
Giuseppe Annunziata, Gian Carlo Tenore, Ettore Novellino
Keywords
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- EP ID EP585367
- DOI 10.32474/ADO.2018.01.000109
- Views 83
- Downloads 0
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