Retrospective Study to Explore a New Predictor for the Early Diagnosis of Perforated Acute Appendicitis

Journal Title: Medical Journal of Clinical Trials & Case Studies - Year 2019, Vol 3, Issue 1

Abstract

Background: Acute appendicitis (AA) is one of the most common indications for emergency abdominal surgery. Objective: To assess diagnostic and prognostic role of serum bilirubin in the management and diagnosis of acute appendicitis, as well as confirming the relationship between them. Methods: A data has been collected about Patients diagnosed with acute appendicitis male and females from the age of 4 up to 80 among king Fahad hospital and East Jeddah hospital during the period from 1st Jan 2012 up to 30th July 2017, with sample size of 888 patients. Results: The study was comprised of 888 consecutive patients. Significance was confirmed as P-value <0.05 Significance was found upon analyzing direct bilirubin for all age groups, total bilirubin for age group less than 15 years, direct bilirubin for 15-20 and 21-30 age groups. Conclusions: Our investigation confirms that bilirubin level might be a biomarker for having appendicitis, it can occasionally differentiate between types of appendicitis, but this is not a sharp ending as it has no role in patients within age groups of above 30 years. However, a problem of specificity is present which hinders the adoption of serum bilirubin as a biomarker foe AA. In addition, several other methods are more specific for the diagnosis and treatment regimen through suitable surgery procedure.

Authors and Affiliations

Shaker AM*, Malik A and Akram B

Keywords

Related Articles

Reversibility of Endothelial Dysfunction Induced by Low Frequency of Electromagnetic Field in Patients with Diabetes Mellitus in Dialysis Extracorporeal

Aims: The life expectancy of patients with Type II Diabetes Mellitus (T2DM) and Diabetic Foot Syndrome (DFS) is dramatically short. The micro-angiopathy, in relation to endothelium dysfunction, decisively affects the va...

Single Ventricle Physiology with Double Outlet and TGA: 3D Cardiac MDCT as a Picture-Perfect Diagnostic Modality

Single ventricle physiology is a cyanotic congenital heart disease that may require intensive medical management after birth. Multidetector computed tomography (MDCT) has recently expanded as advanced imaging modality fo...

Role of Topical Cholecalciferol Therapy in Amputation Stump

Wound healing consists of haemostasis, inflammatory proliferative phases and remodelling phase. A problem with the edge of the wound doesn’t allow healing and causes a delay in the wound healing. In this article, we sha...

Biochemical Studies of Tuberclosis and HIV Cases in Parts of Abia, Anambra and Imo States

Aim: The biochemical of tuberculosis (TB) and (HIV) patients in parts of Abia, Anambra and Imo States, were carried out using, standard biochemical procedures. Methods: Two hospitals were chosen from each of the three St...

Eventration of Diaphragm and Edward Syndrome

Eventration of the diaphragm is an abnormal elevation of the dome of diaphragm. It is a condition in which all or part of the diaphragm is largely composed of fibrous tissue with only a few or no interspersed muscle fib...

Download PDF file
  • EP ID EP755833
  • DOI 10.23880/mjccs-16000195
  • Views 27
  • Downloads 0

How To Cite

Shaker AM*, Malik A and Akram B (2019). Retrospective Study to Explore a New Predictor for the Early Diagnosis of Perforated Acute Appendicitis. Medical Journal of Clinical Trials & Case Studies, 3(1), -. https://www.europub.co.uk/articles/-A-755833