Review and Hypothesis about Gout
Journal Title: Advancements in Cardiovascular Research - Year 2018, Vol 1, Issue 1
Abstract
The first identification about gout as clinical entity was made by the Egyptians in the year 2640 b.C. (Schwartz 2006). For many centuries it was not unveil the mystery of the origin of the illness. Gout is the unique pathology that belongs to the human race. When uric acid is deposited in the articulate tissue produce an intense inflammation, basic element in the development of gout. Interesting is the evidence of ultra sonographic signs of monosodium urate crystalline articulate deposits in 25% of clinically asymptomatic hyperuricaemic subjects (more than 8mg/dL) [1], and approximately 9% of the joints without clinical signs of flogosis [2]. Large epidemiological studies have now demonstrated that gout is an independent risk factor for incident coronary heart disease, [3-6] heart failure, [7] stroke [8] peripheral artery disease [9] and death cardiovascular [10,11]. But, several meta-analyses have concluded that hyperuricaemia is an independent risk factor for coronary heart disease [12,13] and also, for the development of hypertension [14,15]. The standard diagnostic goal remains the identification of the typical birefringence of crystals of uric acid under polarized light microscope in the synovial fluid and in the aspirated material from the tophi [16,17]. Hyperuricaemia with or without urate deposit (modern denomination of the formerly called gout) is currently one of the most frequent dysmetabolic diseases. [18,19].
Authors and Affiliations
Carlos Alberto Paterno Marchioli
Keywords
Related Articles
- EP ID EP586115
- DOI 10.32474/ACR.2018.01.000103
- Views 98
- Downloads 0
HTLV-1 Seropositivity and Unexplained Dilated Cardiomyopathy in Jamaican Patient
Background: Viruses have been implicated in the aetiology/pathogensis of unexplained dilated cardiomyopathy. 6% of adult Jamaicans are HTLV-1 seropositive. We therefore explored the relationship between HTLV-1 infectious...
Acute Viral Myocarditis: The Role of Speckle Tracking Echocardiography
Although, an accurate initial diagnosis of acute myocarditis can be challenging to make, all patients with suspected acute myocarditis need a thorough diagnostic work-up and undergo a full imaging evaluation from the ver...
Extracorporeal Membrane Oxygenation for Failed TPA Therapy of Pulmonary Embolism
Pulmonary embolism may cause cardiac arrest secondary to obstruction of blood flow. Traditional treatment strategies include anticoagulation, thrombolysis, and mechanical extraction. Some advocate for support with extra...
Sleep Quality Disturbances and Blood Pressure Values
The aim of the study was to find out whether early blood pressure (TK) values in patients with fixed and medically treated hypertension correlated with sleep quality during the previous night, and that treatment with ril...
Stimulus Propagation and Left Ventricular Torsion
Introduction and objectives: The ventricular myocardium consists of a continuous muscular band. This anatomy would provide the interpretation for two fundamental aspects of left ventricular dynamics: the mechanism of lef...