Review of Phytochemical, Pharmacological and Toxicological Profile of Stereospermum kunthianum
Journal Title: Journal of Advances in Medical and Pharmaceutical Sciences - Year 2016, Vol 5, Issue 1
Abstract
Aims: The review is directed at the phytochemical, pharmacological and toxicological activities of the medicinal plant Stereospermum kunthianum, Cham, (Bignoniaceae) widely distributed in the Guinean-savannah. Results: A survey of previous scientific publications and available literatures revealed that tannins, saponins, flavonoids, terpenoids, glycosides, sterols, coumarins, quinones and higher fatty acids have been isolated with various solvents from different parts of the plant. Extracts from the plant have shown antibacterial, antiplasmodial, analgesic, anti-inflammatory, antidiarrhoeal, anticonvulsant and antioxidant activities pharmacologically. Sub-acute and acute toxicity studies showed that Stereospermum kunthianum has a wide safety margin up to 1000 mg/kg b. wt. and can be used for long term treatment of disease conditions for which it is indicated. Conclusion: Result emerging from the review of scientific studies unveil the therapeutic potential of Stereospermum kunthianum extracts and isolated compounds thereby justifying the use of the plant in traditional medicine as a remedy for treatment of various diseases in humans.
Authors and Affiliations
J. J. Oloche, F. Okwuasaba, G. O. Obochi
Keywords
Related Articles
- EP ID EP328421
- DOI 10.9734/JAMPS/2016/21743
- Views 126
- Downloads 0
Healthcare-seeking Practices for Common Childhood Illnesses in Northeastern Albania: A Community-based Household Survey
Introduction: Appropriate medical care-seeking could prevent a significant number of child deaths and complications due to ill health. Objectives: The purpose of our study was to assess care-seeking behaviour of mothers...
Comparative Assessment of the Gastrointestinal Tolerability, Anti-inflammatory and Antipyretic Effects of Diclofenac, Ibuprofen and Nimesulide in White Albino Rats
Aim: NSAIDs is among the commonly used drug in the management of disease conditions. The study carried out comparative assessment of gastric tolerability, antipyrectic and anti inflammatory effect of diclofenac, ibuprofe...
Antiretroviral Therapy Contribution to Patients Health in New Juaben Municipality
Our study focused on identifying factors underlining the deteriorating health condition of people living with HIV/AIDS (PLWHA) in the New Juaben Municipality. After a review of the relevant literature, the following hypo...
GC-MS, Antimicrobial and In vitro Antioxidant Assay of the Leaf Extract of Alternanthera dentata
Aims: To evaluate the phytochemical content, antimicrobial and antioxidant activity of the leaf extract of Alternanthera dentata. Study Design: Ethanol was used to extract the plant material for GC-MS analysis and antimi...
Anti-mycobacterial, Antimicrobial and Phytochemical Evaluation of Pulicaria crispa and Scoparia dulcis Plant Extracts
Aim: To examine the antimicrobial activity and evaluate the anti-mycobacterial potency of Pulicaria crispa and Scoparia dulcis whole plant extracts in solvents of different polarities (n-hexane, ethyl acetate and methano...