REVIEW ON A NOVEL APPROACH: MICROSPHERES DRUG DELIVERY SYSTEM
Journal Title: Int J of Pharm Rev& Res - Year 2015, Vol 5, Issue 3
Abstract
There are various approaches in the drug delivering to the target site in a sustained controlled release. One such approach is using microspheres as carriers for drugs which are also known as micro particles. Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers having a particle size ranging from 1-1000μm. The range of Techniques for the preparation of microspheres offers a variety of opportunities to control aspects of drug administration and enhance the therapeutic efficacy of a given drug. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs. The size or average diameter of prepared microspheres were recognized and characterized by scanning electron microscopic methods. The prepared microspheres were found to be spherical and free flowing and remain buoyant for more than 12 hrs .The microspheres having lower densities exhibited good buoyancy effect and hence, these could be retained in the gastric environment for more than12 hrs.
Authors and Affiliations
Vadigoppula Jyothi1 , T. Sri Krishna1 , Ranjtih Reddy Kondeti2
Keywords
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