Review on effect of combination drug therapy on diabetes mellitus and its management
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2014, Vol 2, Issue 1
Abstract
Diabetes is a chronic condition associated with abnormally high levels of sugar (glucose) in the blood. Insulin produced by the pancreas lowers blood glucose. Absence or insufficient production of insulin causes diabetes. An inactive life, which involves lack of exercise and poor calorie management, is one of the biggest contributors to the dreaded disease of diabetes, today. India is facing an epidemic of diabetes. At present, confirmed diabetes patients in India are 67 million, with another 30 million in prediabetes group. By 2030, India will have the largest number of patients in the world. Diabetes is not only a blood sugar problem, but brings along other complications as well. With a person dying and two cases being identified every ten seconds, diabetes is certainly one of the biggest global challenges. And as per WHO report 2012 if India doesn’t awake from its slumber, by 2025, every fifth diabetic on earth would be an Indian. At present there are around 171 million diabetic people all over the world, and India accounts for more than 40 million who are likely to reach 70 million by 2025. Diabetes doesn’t even spare the young Indians as 11.1 % adult males and 10.8 % adult females are suffering from it. Diabetes eventually result sin many fatal diseases such as stroke and heart attack, and, as per WHO estimates, mortality from diabetes including heart disease, kidney failure and others cost India $210 billion in 2005. It would cost India $ 333.6 billion over the decade.
Authors and Affiliations
Sovindra Kumar Bharti, Avantika Srivastava, Ranjeet Singh
PRECLINICAL EVALUATION OF ANTI-DIABETIC AND ANTIHYPERLIPIDEMIC ACTIVITY OF METHANOLIC EXTRACT OF Sterculia foetida LEAVES BY USING WISTAR ALBINO RATS
The Anti-diabetic and Antihyperlipidemic activity of the Methanolic extract of the leaves of Sterculia foetida (jangli badam) (family: Sterculiaceae) was investigated on alloxan induced diabetic albino rats. A comparis...
Protective role of methanolic extract of Polygonum glabrum willd against Cisplatin and Gentamycin induced nephrotoxicity in Albino rats
The nephroprotectic effect of Methanolic extract of Polygonum glabrum willd was studied in Cisplatin,Gentamycin induced Albino Rats. Oral administration of extract to albino rats [200mg/kg and 400mg/kg for 14, 8 days]...
Study on the growth inhibitory effects of Puromycin and Doxorubicin on tumor cell lines (A549, HepG2, HT29 and K562) using Cell Titer-Glo and Alamar blue (Resazurin) based cell viability assays
Cancer is a life-threatening spectrum of diseases in which mortality rates are high. There is more money being spent worldwide on In-vitro cancer research. Cell viability assay is the initial step to develop the antica...
Antimicrobial activity of Vitex leucoxylon, Vitex negundo and Vitex trifolia
In the present study, an attempt was made to investigate the anti-bacterial activity of Vitex leuocoxylon, Vitex negundo and Vitex trifolia. The crude drug powder extracts of the leaves of the above plants were taken f...
A review of various analytical methods on Atrovastatin
There is a review of analytical methods for atorvastatin, such as spectrophotometry, derivative spectrophotometry and various chromatographic procedures such as, high-performance liquid chromatography (HPLC), high-perf...