Review on Transdermal Drug Delivery System: Novel Approches
Journal Title: Scholars Academic Journal of Pharmacy - Year 2018, Vol 7, Issue 9
Abstract
Abstract: Transdermal drug delivery system (TDDS) is one of the novel drug delivery systems coming under the category of controlled drug delivery, in which the aim is to deliver the drug through the skin in a predetermined and controlled rate. Conventional dosage forms have significant drawbacks of poor bioavailability and repeated dosing due to hepatic first pass metabolism. Transdermal delivery has many advantages over conventional drug delivery, it avoids hepatic first pass metabolism, potentially decreases side effects and improves patient compliance. This review gives the idea about anatomy physiology of skin, component of TDDS, advantages and disadvantages, and evaluation test for TDDS. The present drug delivery is highly significant if compared to oral route for less side effect, better bioavailability and longer duration of action. Due to good nature of skin is the greatest challenge that has to be overcome for successfully delivery of the drug molecules to the systemic circulation via this route. This article gives the information of recent trends in the area of TDDS to increase the release pattern of drug and related things which is beneficial for patient.
Authors and Affiliations
Mrs. Ashwini Jadhav, Miss. Shubhangi Vidhate, Mr. Akshay More, Mr. Nikhil Bhujbal, Dr. Sandip Kshirsagar
Keywords
Related Articles
- EP ID EP480367
- DOI -
- Views 90
- Downloads 0
Development and Validation of Dual Wavelength Spectrophotometric methods for Simultaneous Estimation of Ketotifen and Salbutamolin in Bulk and Pharmaceutical Dosage Form
To develop and validate a simple& accurate Spectrophotometry methods for simultaneous estimation of Ketotifen and Salbutamol in their combined pharmaceutical dosage form. Two simple, accurate, precise U.V Spectroscopy me...
Study of Effect of Dexmedetomidineand Clonidine as Adjuvant with Bupivacaine on the onset & Duration of Analgesia and Anaesthesiain Supraclavicular Brachial Plexus Block
Many adjuvants have been used with local anaesthetics to reduce the time of onset and prolong the duration of analgesia in brachial plexus blocks.Very few studies are there comparing dexmedetomidine versus clonidine as a...
Deleterious effects of smoking in male patients in a tertiary care hospital
Abstract:This study explains the deleterious effects of cigarette smoking in patients of SSSMC&RI, Ammapettai. In this study we have collected a history of 75 patients in SSSMC&RI. This history has been collected based o...
Preliminary Phytochemical Screening and Evaluation of Anti-Arthritic Potential of Ledum Pal Mother Tincture using Macrophage Raw 264.7 Cell Lines
Abstract: Rheumatoid arthritis is a chronic inflammatory disease affecting joints manifesting as pain, stiffness, and synovitis leading to articular destruction. Current medical treatments do not consistently halt the lo...
Green Preparation of Jasmine Oil Mediated Bovine Serum Albumin Nanodiscs/nanocubes
The preparations of various metal and polymeric nanoparticles were under scientific considerations these days to get the controllable geometry of prepared nanostructures with the ease of their smallest size at nanoscale....