REY AUDITORY VERBAL LEARNING TEST AS A TOOL FOR DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT
Journal Title: Acta Neuropsychologica - Year 2008, Vol 6, Issue 2
Abstract
[b]Background.[/b] Previous research suggests that patients with Alzheimer's disease (AD) manifest more false alarm (FA) responses in recognition memory tests than patients with Huntington disease (Delis et al., 1991), minimal cognitive impairment (MCI) or normal controls (Greenaway et al., 2006). It has been shown that 50% of patients with MCI develop dementia within 5 years (Gauthier et al., 2006). An early diagnosis of MCI when treatment is most effective is thus warranted. The objective of this study was to characterize recognition memory error patterns in patients with MCI in order to predict an incipient AD.[b]Methods.[/b] 33 MCI patients whose MMSE scores were between 25 and 27 participated in the study and were compared to 97 TLE patients who underwent full neuropsychological evaluations. FA measure was applied to analyze the recognition memory errors on the Rey Auditory Verbal Learning Test (RAVLT).[b]Results.[/b] According to the independent sample t-test, MCI patients demonstrated significantly more FA errors than TLE patients (p=0.01). A significant negative correlation between the number of FA mistakes and the score on the MMSE was found in the MCI group (p=0.04).[b]Conclusions.[/b] The present findings suggest that a high number of FA errors, in a framework of a comprehensive neuropsychological evaluation, may be helpful in an early diagnosis of MCI.
Authors and Affiliations
Yohai Zeidman, Avraham Schweiger, Amos Korczyn, Veronika Vachapov, Ruth Verhovsky, Ilan Halperin, Miri Neufeld, Itzhak Fried, Fani Andelman
Keywords
Related Articles
- EP ID EP55294
- DOI -
- Views 148
- Downloads 0
SOCIAL INTELLIGENCE MONITORING IN PATIENTS WITH ORBITOFRONTAL CORTEX INJURY
[b]Background.[/b] The orbitofrontal cortex is responsible for self-awareness, behavior control, the ability to adapt one's actions to the current situation and social rules, and comprehending another person's state of m...
THE LOGOPEDIC EXAMINATION OF PATIENTS WITH ALZHEIMER’S DEMENTIA
Background: A valuable source of information on a patient’s mental condition in dementia cases is an assessment of their narrative skills. In the course of a logopedic examination special attention should be focused on t...
ON THE MICROGENOGESIS OF SCHIZOPHRENIA
The theory of microgenesis, as described by Jason Brown and others, involves the hierarchical elaboration of the self and object world from a deep core of self, from unconsciousness to consciousnesss, through a simultane...
Portrait of a scholar: Jason Walter Brown
This biography presents a half century of the commitment of Prof. Jason W. Brown, M.D., to the development of neurology, neuropsychology and philosophy of mind. For over 30 years clinical professor of neurology at New Yo...
Badanie EEG wraz z potencjałem P300 jako metoda do sprawczego różnicowania pacjentów z uwarunkowaniem genetycznym i środowiskowym uzależnienia od alkoholu
Charakterystyka elektrofizjologiczna alkoholików, w postaci amplitudy P300 w zakresie potencjałów indukowanych (ERP), jest związana z wysokim ryzykiem alkoholizmu u potomstwa i uważa się ją za biologiczny endofenotyp pre...