Role of Antioxidant-Rich Nutraceutical on Body Weights and Mean Arterial Blood Pressure of Salt-Induced Hypertensive Rats
Journal Title: International Journal of Biochemistry & Physiology - Year 2017, Vol 2, Issue 1
Abstract
Hypertension or high blood pressure is a medical condition in which blood pressure in the vessels is persistently elevated. The study aim to formulate an antioxidant rich nutraceutical from locally available food stuff (onion, garlic, ginger, tomato, lemon, palm oil, water melon seeds) and investigate their effects on blood pressure and body weight in salt-induced rats. The rats were placed on 8% salt diet for 6 weeks and then supplementation and treatment with nutraceutical and nifedipine in the presence of salt diet for additional 4 weeks. Feeding rats with salt diet for 6 weeks increased blood pressure and body weight of the salt-loaded rats relative to control. Both supplementation and treatment (nifedipine) lowered the blood pressure but only supplementation lowered the body weight. Antioxidantrich nutraceutical might be beneficial in the managements of patients with hypertension and obesity.
Authors and Affiliations
Lawal N
Keywords
Related Articles
- EP ID EP396066
- DOI 10.23880/ijbp-16000114
- Views 91
- Downloads 0
Nitric Oxide Molecule and Human Cancers
Nitric Oxide (NO) is a short-lived, endogenously produced free radical that is synthesized by the enzyme nitric oxide synthase conversion during arginine to citrulline and serves as a key signalling molecule in various p...
Biochemical Characterization of Two Major Proteins of the Hamster Sperm Acrosomal Matrix
An acrosomal fraction, termed the ALM (acrosomal lamina complex) was isolated from hamster cauda epididymal spermatozoa that contain specific domains of the acrosomal matrix and an adherent detergent-insoluble complex, t...
Evaluation of Anti-Hyperglycaemic Potential of Allium Cepa, Coffee and Oxidative Stress
Allium cepa Linn, botanicals, Liliaceae (family) commonly known as onion, and coffee are special delicacies, and conventional as functional foods that contain physiologically active ingredients that for centuries have be...
Study Kidney Functions, Body Weight, Blood Pressure in Patients with Pregnancy Induced Hypertension (PIH)
An aim of this study is to assess weight, pressure and kidney functions of healthy (control) and patient with PIH (eclampsia). Data was collected by using structured questionnaire. Body weight was measured to an accuracy...
Uric Acid as a Biomarker of Metabolic Syndrome in Sudanese Adults
Serum uric acid (SUA) is considered as a component and a marker of metabolic syndrome (MetS). Our aim is to investigate the prevalence of hyperuricemia and its relationships to MetS and its components such as hypertensio...