Role of Circulating C Reactive Protein in Thyroid Disorders
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 2
Abstract
Introduction: High sensitive C– reactive protein (hs-CRP) is an important sensitive inflammatory marker. Serum level of hs-CRP is not a routine investigation parameter to diagnose thyroid disorders, although many thyroid conditions involve inflammation. In the present study, the level of the hs-CRP and its association with thyroid disorders were assessed. Material & Methods: A total of 92 males and 112 females, from the age group of 20 to 55 year were selected for the study. Estimation of hs-CRP was done on semi auto analyzer (Robonikread well touch ) by Enzyme immunoassay technique, the serum was also assayed for T3, T4 & TSH by enzyme linked fluorescence assay ( ELFA) technique using Vidas auto –analyzer. Result: In our study we have found the Value of T3 in cases is 1.13± 0.88 nmol/L is high as compared to control group value 1.04± 0.28 nmol/L, Value of T4 in cases is 90.64 ±59.87 nmol/L as compared to control group value 92.47± 12.91 nmol/L, Values of TSH in cases is 7.15± 6.58 mIU/L is very high as compared to control group value 2.27 ±1.06 mIU/L. During our study we have also found values of hs CRP in cases 2.86± 0.97 mg/L as compared to control 1.89 ±0.62 mg/L Conclusion: Our study findings suggest that abnormal thyroid hormones level interfere with the serum levels of hs–CRP which can have the implications related to Cardio vascular diseases.
Authors and Affiliations
Prof. Suryakant Nagtilak
Keywords
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