Role of Insulin Aspart in Management of Diabetic Ketoacidosis.
Journal Title: PARIPEX-Indian Journal of Research - Year 2015, Vol 4, Issue 7
Abstract
Introduction: Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes. Recently, new analogues of human insulin aspart are used in treatment of mild to moderate diabetic ketoacidosis. AIM: To study the role of subcutaneous insulin aspart in management of diabetic ketoacidosis. Results: The mean duration of treatment until glucose concentration was <13.8 mmol/l (<25omg/dl) was not statistically different between patients treated with SC-1h (6.8 + 3h) and SC-2h (6.5+ 3h) or with IV regular insulin (6.9 + 4h). Similarly, the mean duration of treatment until resolution of ketoacidosis was not statistically different among treatment groups 10.3 + 3, 10.8 + 3 and 10.5 + 3 h respectively. Conclusions: Treatment with subcutaneous insulin aspart 1 hourly/2hourly represent a safe and effective alternative to intravenous regular insulin in mild to moderate form of diabetic ketoacidosis.
Authors and Affiliations
Dr. Anurag Prasad, Dr. Anubhav Gupta
Keywords
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