Role of Ketamine as an Adjuvant to Bupivacaine in C-Arm Guided Thoracic Paravertebral Block Analgesia for Modified Radical Mastectomy
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 71, Issue 5
Abstract
<span>Background: </span><span>Breast cancer is the most common type of cancer found in women and today represents a significant challenge to public health. Postoperative pain is the most distressing symptom experienced by the patient. Pain induces metabolic, hormonal and cardio-respiratory responses that affect the outcome of surgery.<br /> </span><span>Aim of the Work: </span><span>The aim of this study was to evaluate the role of ketamine as an adjuvant to bupivacaine in c- arm guided thoracic paravertebral block analgesia for modified radical mastectomy. </span><span>Patients and Methods: </span><span>This study was carried out in Tanta University Hospitals in Surgery Department from April 2016 to October 2016 on sixty-two patients scheduled for elective modified radical mastectomy divided into two equal groups each contain 31 patients, group 1 received PVB with bupivacaine only under c arm and group 2 received PVB with bupivacaine and ketamine as pre emptive analgesia and watch what is the outcome. Written informed consent was taken from each patient. </span><span>Results: </span><span>This prospective randomized double blind study was carried out on 62 patients divided into two equal groups where group two showed statistically significant decrease in VAS , total amount of analgesic and delay in time of first analgesic requirement in comparison with group one and significant difference as regard hemodynamics and postoperative complication between two groups. </span><span>Conclusion: </span><span>We concluded that addition of ketamine to bupivacaine as an adjuvant in C-arm guided PVB appears to be more beneficial than the use of bupivacaine alone for postoperative analgesia in modified radical mastectomy surgery.<br /> </span>
Authors and Affiliations
Eman Helal
Keywords
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