Role of MRI and Doppler Sonography in Evaluation of Soft Tissue Masses: A Comparative Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 5
Abstract
Introduction: MRI is well established to provide excellent spatial and anatomical evaluation of soft tissue masses, however grey scale and Doppler evaluation may provide sufficient information to differentiate benign and malignant soft tissue tumours in good number of cases. Objective: The objective of the study was to compare the role of grey scale and Doppler USG and MR imaging in soft tissue masses and correlating the diagnosis with final diagnosis based on histopathology for distinguishing benign from malignant soft tissue masses. Material and Methods: The study was conducted in 25 patients presenting with soft tissue swelling on clinical examination. The patients were first subjected to sonographic evaluation followed by MRI. The results were compared with the final diagnosis established by histopathological / FNAC examination. Results: For malignant masses, USG had 86% sensitivity, 100% specificity with a positive predictive value of 100% and a negative predictive value of 85%. For benign masses, USG had 100% sensitivity, 86% specificity with a positive predictive value of 85% and a negative predictive value of 100%. For malignant masses, MRI had 93% sensitivity, 100% specificity with a positive predictive value of 100% and a negative predictive value of 92%. For benign masses, MRI had 100% sensitivity, 93% specificity with a positive predictive value of 92% and a negative predictive value of 100%. Conclusion: Purely cystic & nonvascular masses can be simply followed with serial USG or subjected to surgery without histopathology and further imaging. Large masses with PSV >50 cm/s, RI <0.5, irregular areas of calcification that are suspicious for malignancy may be subjected for MRI for presurgical detailed evaluation and staging. Final diagnosis of many benign masses like lipomas, nerve sheath tumors, haemangiomas, paragangliomas & soft tissue hydatid can also be highly suggested on MR imaging, which was slightly more sensitive than USG for benign as well as malignant masses.
Authors and Affiliations
Dr Ashwani Tomar
CD 4 Response in HIV Patients on Long Term First Line ART – A Cross Sectional Study from South India
The CD4 count is the most important indicator of immune function in HIV-infected patients. It is also the strongest predictor of subsequent disease progression and survival. We conducted a study to estimate the CD4 count...
Seroprevalence of Hepatitis B in replacement and voluntary blood donors at Tertiary care center, M.Y.H. Indore
Background: Blood transfusion is a potentially significant route of transmission of infections to the recipient. Objective: The aim of study is to determine the seroprevalence of Hepatitis B among replacement and volunta...
To Study the Ocular Side Effect by Chronic Use of Steroid in Chronic Obstructive Pulmonary Disease (COPD) Patients Attending Tertiary Care Centre in North India
Objective: To study the Ocular side effect by chronic use of steroid in Chronic obstructive pulmonary disease (COPD) attending tertiary care center in north India Method: 500 COPD patients of age group 50 -90 years with...
Study of Refractive Errors, Amblyopia and Compliance of Spectacles in School Children
Objective: 1. To estimate the prevalence of refractive errors in school children (6-17yrs) and to categorize them. 2.To find out the prevalence of amblyopia in school children. 3.To study the compliance of spectacle use...
Determining Inducible Clindamycin Resistance in Staphylococcus Aureus from Various Clinical Samples by D-Zone test with Special Reference with MRSA
Clindamycin is used in the treatment of skin and soft tissue infections caused by staphylococcus aureus and also alternative for patients who are allergic to penicillin. Treatment of an infection caused by as strain carr...