Role of platelet rich plasma in patients of osteoarthritis knee-a prospective study
Journal Title: Indian Journal of Orthopaedics Surgery - Year 2017, Vol 3, Issue 2
Abstract
Introduction: In the present study, we evaluated the effects of 2 courses of PRP injections with 3 weeks interval, on patient's quality of life and functional ability. Materials and Method: It was a prospective study carried out on 55 patients (14 males & 41 females) in the Department of Orthopedics’, Era’s Lucknow Medical College, Lucknow, and Uttar Pradesh from Sep 2015 to March 2016. Age >40 years, Knee arthralgia (>3 months) and Radiologic evidence of articular damage (grades 1-3 of Kellgren-Lawrence scale) based on knee Osteoarthritis criteria of American College of Rheumatology were enrolled in our study. Two intra-articular injections of Platelet Rich Plasma (PRP) at 3 weeks interval was given and patient was regularly followed up after 3rd week, 6th week, 3 months & 6 months of the 1st injection Results: Mean scores of all WOMAC parameters improved significantly compared to before treatment. Each Parameter of the WOMAC Score was compared with baseline score at each follow-up. Reduction in the mean pain, mean physical function and mean total womac scores from base line scores were observed during the course of 1st (3 weeks) &2nd (6 weeks) follow-ups then after marginal increase in scores were reported during 3rd (3 months) and 4th (6 months)follow ups but difference in mean of all scores were significant with the respective base line scores. Conclusion: The results of our study showed that intra-articular knee injections of Autologous Platelet Rich Plasma (PRP) are effective in reducing joint pain, stiffness and improve knee functions in early knee Osteoarthritis.
Authors and Affiliations
Farid Mohammed, Varun Aggarwa, Sudhir S Kushwaha, Amit Verma, Yasir Ali Khan
Keywords
Related Articles
- EP ID EP293877
- DOI 10.18231/2395-1362.2017.0033
- Views 98
- Downloads 0
Management of both forearm bone diaphyseal fractures - ORIF v/s CRIF v/s hybrid fixation: An operative dilemma
Introduction Long bone fracture of forearm is common skeletal injury The most common causes of such injuries include road traffic accident fall or direct trauma amongst the various types of forearm fractures bothbone dia...
Comparative study between functional outcome of closed and open percutaneous K-wire fixation in gartland type II and III extension type supracondylar humerus fractures in children
Background: Supracondylar fractures of humerus is one of the most common injuries in children. It requires great attention while treating as it is associated with neuro-vascular complications pre-operatively and intra-op...
Comparison of outcome of distal humerus fracture: Single extra articular humerus plating versus bipillar plating
Introduction Distal humerus fractures are complex injuries as their management requires stable fixation and properly working adjoining joints Management includes open reduction and internal fixation of distal humerus fra...
“Evaluation of patient satisfaction after total hip arthroplasty”
Background: Nowadays Total Hip Arthroplasty is the final treatment option provided to patients with unsalvageable, severely arthritic, painful and deformed hips. Arthroplasty has evolved over a period of many years.(1-5)...
Evaluation of results of fracture Proximal Humerus treated with Kirschner Wire and mini external fixation
Fracture of Proximal humerus are most common humerus fracture (45%). These are more common than hip fracture. As the patient has a direct fall on the limb these fractures are mostly undisplaced (85%). These are more comm...