Routine Histopathological Analysis of Non-suspicious Looking Foreskin for Adult Patients: Is It Necessary?

Journal Title: Journal of Advances in Medical and Pharmaceutical Sciences - Year 2017, Vol 15, Issue 3

Abstract

Objective: To evaluate the routine histopathological analysis of foreskin in adult patients and determine whether histological processing is necessary in patients with non-suspicious foreskin. Materials and Methods: All adult foreskin sent for histopathological analysis between September 2014 and February 2016 at a single institution (Leighton hospital) was included in this study. Histology was compared to macroscopic appearances. A cost analysis was performed. Results: There were 262 specimens of foreskin sent for histopathological analysis between September 2014 and February 2016. The average age for patients was 48.5 years. Most cases showed chronic inflammation, (n=110, 42%). No cancer was identified in macroscopically non- suspicious looking foreskin. Clinically diagnosed balanitis, xerotica obliterans and suspicious looking foreskin was predictive of histological abnormality. Conclusion: Sinister pathology was not identified in non-suspicious specimens. We recommend that foreskin of patients with a high risk for penile malignancy, and macroscopically abnormal looking foreskin should always be sent for histological analysis.

Authors and Affiliations

N. Kadi, L. Kayali, A. S. Bates

Keywords

Related Articles

Hemodialysis-associated Oxidative Stress: Comparison of Helixone® and Polysulfone® Dialyzer

Background: Patients at end stage renal failure require hemodialysis, a process that contributes to oxidative stress, where the quality of hemodialysis membrane plays a key role. Aim of the Study: We sought to investiga...

Adverse Haematological Changes in Plasmodium Infected Mice Following Treatment with Azadirachta indica (Neem) Leaf Extract

Background: Azadirachta indica (neem) is an effective natural remedy for malaria treatment in some tropical regions of Africa. This study investigated the impact of Azadirachta indica leaf-extract on some haematological...

Effects of Acetylsalicylic Acid and Salicylic Acid on the Growth of HeLa Cervical Cancer Cells Line

Introduction: Cervical cancer is the fourth most common cancer affecting women in the world, 527,000 new cases were reported and over 250,000 deaths were reported each year. The major risk factor of cervical cancer is in...

Hepatitis B Vaccination Coverage and Knowledge among Healthcare Workers at a Tertiary Hospital in Jeddah, Saudi Arabia

Background: Healthcare workers in tertiary hospital are at the risk of exposure and possible transmission of hepatitis B virus (HBV) infection. This infection is a major and important occupational hazard among health car...

Monosodium Glutamate Induced Hepatotoxicity and the Possible Mitigating Effect of Vitamin C and Propolis

Monosodium Glutamate (MSG) has been recognized as a relish additive that adversely affects liver function's parameters. The aim of this study was to assess the effects of MSG on the liver enzyme markers, lipid profile an...

Download PDF file
  • EP ID EP313226
  • DOI 10.9734/JAMPS/2017/38117
  • Views 74
  • Downloads 0

How To Cite

N. Kadi, L. Kayali, A. S. Bates (2017). Routine Histopathological Analysis of Non-suspicious Looking Foreskin for Adult Patients: Is It Necessary?. Journal of Advances in Medical and Pharmaceutical Sciences, 15(3), 1-5. https://www.europub.co.uk/articles/-A-313226