Safety and Efficacy of Eczero® (Ochrocarpus longifolius) Cream in the Treatment of Mild to Moderate Eczema - An Open Label, Phase II, NonComparative Study

Journal Title: Journal of Clinical and Investigative Dermatology - Year 2018, Vol 6, Issue 2

Abstract

Background: Eczero® cream is developed from Ochrocarpus longifolius plant extract studied for its anti-bacterial and antiinflammatory properties. Objective: To evaluate the safety and efficacy of Eczero® cream in treatment of mild to moderate eczema. Method: This was an open label, non-comparative, phase II, clinical trial conducted in 44 patients. The treatment was given for a period of 28 days. Overall eczema severity was assessed by using local SCORAD index, VAS score for itching and patient and physicians global assessment of therapy. Results: Application of Eczero® cream showed significant reduction in edema, erythema, lichenification and oozing with an overall improvement in the eczema lesions. The cream was well tolerated with no serious adverse events observed. Conclusion: Eczero® cream can be considered as a possible therapeutic option for the treatment of mild to moderate Eczema in adults.

Authors and Affiliations

Kavita Salkar

Keywords

Related Articles

A Case of Giant Molluscum Contagiosum in an Immunocompetent Child

A 4-year-old boy presented with an asymptomatic, erythematous mass on the abdomen. His mother said that the lesion developed a few months ago and have been gradually increasing in size. His weight was 19 kg, height was 9...

Silicone Granulomas in the Setting of Acupuncture with Silicone-Coated Needles

Silicone is widely used in various capacities in medicine including aesthetic and prosthetic joint implants as well as in the coating of vials, catheters, drains, shunts, and needles [1]. Silicone-coated needles have bec...

Recent Statistics on Atopic Dermatitis in Korea: Five-Year Nationwide Analysis from 2008 to 2012

Background: Most of the previous epidemiologic studies on atopic dermatitis were based on the analysis of young patients excluding adults, and the target population was confined to a certain area. Korea has a national he...

Systemic Lupus Erythematosus:Immunologic Profile According to Clinical Manifestations in 30 Patients in the University Hospital of Cotonou, Benin

Objective: It aims to describing the profile of antinuclearautoantibodies and their association with the clinical manifestations ofSystemic Lupus Erythematosus (SLE). Methods: A 15-year and 7-month retrospective, analyti...

Reversible Nail Discoloration from Hydroquinone 4% Cream

Introduction: Hydroquinone is a tyrosinase-inhibiting phenolic compound widely prescribed for disorders of pigmentation such as melasma, lentigines and post inflammatory hyper pigmentation. Well-known adverse effects of...

Download PDF file
  • EP ID EP496647
  • DOI 10.13188/2373-1044.1000053
  • Views 113
  • Downloads 0

How To Cite

Kavita Salkar (2018). Safety and Efficacy of Eczero® (Ochrocarpus longifolius) Cream in the Treatment of Mild to Moderate Eczema - An Open Label, Phase II, NonComparative Study. Journal of Clinical and Investigative Dermatology, 6(2), 1-6. https://www.europub.co.uk/articles/-A-496647