Screening for Nasal Carriage of Mupirocin Resistant Staphylococcus aureus among health care workers in a tertiary care hospital
Journal Title: Indian Journal of Microbiology Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction: The aim is to isolate and to identify Staphylococcus aureus from the nasal swabs of the health care workers and screen for the mupirocin resistance among the isolated Staphylococcus strains. Materials and Methods: Present study is a prospective type of study. A total of 100 nasal swabs were collected from health care workers. All the nasal swabs were cultured on MacConkey and Blood agar. Isolated organisms were subjected for antibiotic susceptibility testing by Kirby-Bauer disk diffusion method. Results: Among the 100 nasal swabs, Staphylococcus spp. was isolated in 100 (100%) samples which comprised of 13 (13%) Staphylococcus aureus isolates and 87(87%) were Coagulase negative Staphylococcus. Of 13 Staphylococcus aureus isolates, 7 (53.84%) and 6 (46.15%) were detected as Methicillin Resistant Staphylococcus aureus and Methicillin Sensitive Staphylococcus aureus respectively. None of S.aureus isolates was resistant to mupirocin. Low level mupirocin resistant (MupL) was seen in 10 (30%) of Methicillin Resistant Coagulase negative Staphylococcus and 5 (14.7%) in Methicillin Sensitive Coagulase negative Staphylococcus isolates, respectively. High level mupirocin resistant (MupH) was seen in 4 (12%) of Methicillin Resistant Coagulase negative Staphylococcus and 4 (12%) of MRCoNS and MSCoNS isolates, respectively. Conclusion: Mupirocin is a potent antibiotic to treat the nasal carriage of S. aureus. As resistance to mupirocin both low and high level is on rise, it is a matter of great concern. Policies and guidelines should be framed to create awareness among the health care workers regarding the screening methods for the detection and treatment of nasal carriage.
Authors and Affiliations
Elanithi K, Kavitha E, Joshy M Easow
Keywords
Related Articles
- EP ID EP473000
- DOI 10.18231/2394-5478.2018.0050
- Views 70
- Downloads 0
Catheter associated urinary tract infection(CAUTI)– Incidence and microbiological profile in a tertiary care hospital in Andhra Pradesh
Background: The etiological agents of Catheter associated urinary tract infection (CAUTI) are sundry and often multidrug resistant. An early, appropriate antimicrobial therapy based on culture sensitivity report and impl...
Different Methods of Staining to optimize Smear Microscopy for Diagnosis of Pulmonary and Extra Pulmonary Tuberculosis
Introduction: Tuberculosis continues to be a major public health problem especially in low income and high incidence countries like India. Aim of the study was to access and compare sensitivity and specificity of Light...
Isolation, purification and characterisation of bacteriocin producing Lactobacillus species and its antimicrobial efficacy against food borne pathogens
Lactobacilli are a group of bacteria that are ubiquitous and contribute to the normal microbial flora of human beings. They are Generally Regarded as Safe (GRAS) and are not lethal to host. Bacteriocins are ribosomally s...
Mupirocin and vancomycin susceptibility in MRSA colonising anterior nares of patients scheduled for cardiac surgery
Background: Mupirocin has been recognised as the best and the most effective topical antimicrobial agent for decolonisation. With widespread use of mupirocin for decolonisation, increasing number of MRSA have developed r...
A study on knowledge, attitude and practice of biomedical waste management among health care workers in a Tertiary Care Hospital in Puducherry
Introduction Health care workers HCWs are constantly associated with generation segregation and disposal of biomedical wastes BMW Knowledge attitude and practice KAP of BMW management among HCWs are the three determinant...