Screening for Thyroid Function During First Trimester of Pregnancy- Should it Be Made Mandatory

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Screening for Thyroid Function During First Trimester of Pregnancy- Should it Be Made Mandatory

Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 8

Abstract

Our study was an outpatient department (OPD) based cross sectional study. During the study period, 500 antenatal cases were screened for thyroid function at their first trimester between the age group of 18 to 35 years. Serum thyroid-stimulating hormone, FT3, FT4 estimation was done by the Chemiluminescence assay method. We have followed the recent Endocrine Society guidelines for thyroid dysfunction. Our study emphasizes the need of universal screening of thyroid function during first trimester of pregnancy by screening the antenatal cases in their first trimester .We also calculated the prevalence of thyroid disorder. The overall prevalence of thyroid disorder was found to be 49.20%. Out of 500 pregnant lady 213 (42.60% %) was suffering from subclinical hypothyroidism with mean TSH level 3.924 ±1.06mIU/ml, and 21(4.2 %) were suffering from overt hypothyroidism with mean TSH 7.325 ± 0.968mIU/ml. 9 cases were suffering from subclinical hyperthyroidism with mean TSH 0.042±0.026 and only 3 cases were suffering from overt hyperthyroidism. Rest 254 50.8%) were euthyroid with mean TSH level 1.5±0.48mIU/ml. The mean age of the study population was 25.07 ± 4.33 years. In our study we found that 46.8 % pregnant women in first trimester was suffering from hypothyroidsm. Thyroid disorders are common in pregnancy, and the most common disorder is subclinical hypothyroidism. Even though universal TSH screening is not yet recommended, it should be considered in view of results shown by different studies and our study. Keywords: Thyroid-stimulating hormone, Pregnancy, Hypothyroidism, Hyperthyroidism, FT3, FT4

Authors and Affiliations

Saroj Jhuria, Reeta Bhuyan, Gokul Chandra Das

Keywords

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