Sensitivity of Candida albicansto aqueous and alcohol extracts of four medicinal plants
Journal Title: Journal of Ayurvedic and Herbal Medicine - Year 2017, Vol 3, Issue 3
Abstract
Candida albicansadimorphic fungus that exists as a commensal of warm-blooded animals including humans. Candida albicans infection raises a number of challenges including resistance of Candida albicans to the commonly used antifungaland the higher cost of the antifungal agents.The aim of this study is to test the fungus Candida albicans sensitivity to some medicinal plants namely, Solenostemma argel (Hargel), Matricaria chamomilla (Chamomile), Origanum majorana (Marzanjosh) and Guiera senegalensis (Gebbish). The pure culture of the fungus was obtained from the Medical laboratory - University of Gezira, Sudan. The plants were obtained from Wad Medani herbal local market. Both aqueous and alcoholic extracts were prepared from the four herbs (20%, 35% and 75%) concentrations and (2%,3%,4%,5%,6% and 10%). The sensitivity was tested, using the disc diffusion test that measures the inhibition zones produced by the different herbs at the different concentrations and extraction methods used against the C.albicans. The anticandidal activity ofthe aqueous extract of the different herbs did not detect, regardless of the concentration used, while the alcoholic extracts showed remarkable anticandidal activity and the herbal plant Guiera senegalensis gave thehighest inhibition (14.3mm) at the highest concentration (10%), followed by Matricaria chamomilla with an average inhibition zone of 14 mm andSolenostemmaargelwith average inhibition zone of 13 mm and Origanum majorana with average inhibition zone of 12.6 mm. Significant differences were found between the four herbs at the different concentrations (P value = 0.002).Moreover, increasing the concentration was found to improve the antifungal activity of the herbs and gave better fungal inhibition.Further studies are recommended to investigate the role of the different extraction solvents on the efficiency of the herbs.
Authors and Affiliations
Mai Abdalla Ali, Ahmed Faroug Mohammed Alhag, Awad Mohamed Abdel-Rahim
Keywords
Related Articles
- EP ID EP596178
- DOI -
- Views 92
- Downloads 0
Ayurvedic approach to floating harbor syndrome: A case report
Floating-Harbor syndrome (FHS) is an extremely rare genetic disorder characterized by a distinctive facial appearance, various skeletal malformations, delayed bone age, and expressive and receptive language delays. Child...
Effective Ayurveda therapy to treat thyroid disorders
Introduction: Thyroid disorders are on the rise across the world. While there are therapies available to treat them, many unavoidable side effects occur as part of the therapy. Ayurveda is the ancient system of medicine...
Phytochemical analysis of successive extracts of the Cordia macleodii leaves Hook.: A Folklore medicinal plant
‘Preliminary phytochemical analysis of successive extracts, fluorescence analysis and HPTLC of C. macleodiileaves has been planned in the current study.’ The extracts of the dried coarse powdered of C. macleodii leaves o...
Lifestyle consequences on Ageing: A survey study
To remain healthy and happy for hundreds of year with all good functioning sensoria is a basic cherish wish of human since era. In other hand ageing and death are natural and inevitable diseases. Ageing is a physiologica...
A conceptual review of Warme Rehm in Unani Medicine with specific reference to pelvic inflammatory disease
Pelvic inflammatory disease (PID) is the most common infections of female reproductive organs, which can occur in sexually active women during the reproductive age & remains an important public health problem. PID is dia...