Seroepidemiological study of toxoplasmosis in hemodialysis patients of Ahvaz, Southwest of Iran
Journal Title: International Journal of BioMedicine and Public Health (IJBMPH) - Year 2018, Vol 0, Issue 0
Abstract
Introduction: Toxoplasma gondii infects most warm-blooded vertebrates. Because of the immunodeficiency in hemodialysis patients, these individuals are at higher risk for reactivating chronic toxoplasmosis. Thus, the aim of this study was to investigate seroepidemiology of toxoplasmosis in hemodialysis patients of Ahvaz, southwest of Iran during 2015-2016. Methods: This is a cross-sectional study. A total of 160 participants, 80 hemodialysis patients (test group) and 80 healthy persons (control group) were randomly selected. IgG and IgM against T. gondii was measured by CLIA (Chemiluminescence) and ELISA (Enzyme-linked immunosorbent assay) tests. To analyze the data from Chi-square test, and SPSS statistical software of version 21 was used. Results: In hemodialysis patients, 35 (43.8%) and 25 (31.3%) were positive for the antibody of IgG by ELISA and CLIA, respectively. In healthy individuals, a positive result of 22 (27.5%) and 13 (16.3%) were obtained by ELISA and CLIA, respectively. In hemodialysis patients, 5 (6.3%) and 4 (5%) was positive by ELISA and by CLIA, respectively. In healthy individuals, a positive of 4 (5%) were obtained by ELISA and CLIA. The antibodies of IgG in hemodialysis patients was significantly higher than healthy individuals by ELISA and CLIA (P <.05). Conclusion: The prevalence of Toxoplasma in hemodialysis patients was higher than healthy subjects. Our finding showed a relatively high prevalence of the parasite among hemodialysis patients and healthy individuals in Ahvaz. So, the health authorities of Ahvaz city must pay more attention to control of the infection, especially in hemodialysis patients.
Authors and Affiliations
Forough Kazemi, Somayeh Fallahizadeh, Mohammad Hosein Feizhadad
Keywords
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- EP ID EP262260
- DOI 10.22631/ijbmph.2018.55340
- Views 112
- Downloads 0
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