SEROPREVALENCE OF CO-INFECTIONS AMONG BLOOD DONORS AT THE BLOOD BANK OF A TERTIARY CARE HOSPITAL, IN SOUTHERN INDIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 38
Abstract
BACKGROUND Transfusion Transmissible Infections (TTIs) like HIV, HBV, HCV, syphilis and malaria are major problems associated with blood transfusion practices. Because of shared modes of transmission, co-infection with HIV, HBV and HCV is a significant occurrence. Apparently, healthy blood donors may carry double viral co-infections that might be more fatal than viral mono-infection for the donor himself as well as recipient later on. Hence the study was undertaken to analyse the prevalence and patterns of coinfections among blood donors in our geographical area. MATERIALS AND METHODS All blood donors attending to the blood bank at Anam Chenna Subba Reddy (ACSR) Government General Hospital, Nellore during the period January 2013 to December 2017 were screened for hepatitis B surface antigen (HBsAg), anti HCV antibody, anti-HIV-1, 2 antibodies by using the appropriate Enzyme-Linked Immuno-Sorbent Assay (ELISA) method and further confirmed using an ELISA kit from a different manufacturer. The Rapid Plasma Reagin (RPR) test was used for estimation of syphilis infection. RESULTS Of the 11,234 donors who were screened during the study period, 10 (0.08%) were reactive for different combination of infections. The various combination of infections seen were as follows; HIV + HBV (5/10), HBV + HCV (3/10), HIV + HCV (1/10), and HIV + Syphilis (1/10). CONCLUSION Effective control strategies including a stringent screening of all blood donors, public awareness programs and institution of adequate public health measures are urgently needed.
Authors and Affiliations
Sindhuja Kondareddy
Keywords
Related Articles
- EP ID EP572252
- DOI 10.18410/jebmh/2018/558
- Views 94
- Downloads 0
KNOWLEDGE AND PRACTICE OF CONTRACEPTIVE USE AMONG THE ELIGIBLE COUPLES IN AN URBAN SLUM OF SAMBALPUR
In spite of implementation of various programs and policies to curb the population of India, the population growth of India continues to be high in the count of large size of population (58% of total population) in the r...
COMPARATIVE STUDY BETWEEN FNAC AND CYTOPUNCTURE FINDINGS IN CERVICAL LYMPHADENOPATHY
BACKGROUND The aim of this study was to compare diagnostic accuracy of Cytopuncture with Fine Needle Aspiration Cytology (FNAC) in cervical lymphadenopathy. MATERIALS AND METHODS This is a prospective study conducted on...
RHINOSCLEROMA OF LARYNX: A CASE REPORT
Rhinoscleroma is a chronic granulomatous disease of the respiratory mucosa caused by klebsiella rhinoscleromatis. It commonly involves the nose followed by nasopharynx, oropharynx, larynx, trachea and bronchi. Middle age...
COLLISION TUMOR OF THE THYROID: AN UNCOMMON ENTITY
INTRODUCTION: Collision tumor of the thyroid is the presence of histopathologically distinct tumors within the thyroid. The concomitant presence of both papillary and squamous cell carcinoma within the thyroid is an unco...
UNDIAGNOSED THANATOPHORIC DYSPLASIA AT TERM- OBSTETRICIAN’S DILEMMA!!- A CASE REPORT
BACKGROUND Thanatophoric Dysplasia (TD) is a lethal skeletal dysplasia. Prenatal diagnosis of TD is usually accomplished by Ultrasonography (USG). However, it is not always possible to distinguish TD from other skeletal...