Seroprevalence of HBV, HCV and HIV infection among blood donors at a tertiary care center in Eastern India- Time to introduce molecular methods for follow up management of all seropositive donors
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 6
Abstract
The important transfusion transmitted viruses in India are, human immunodeficiency virus (HIV-I/II), hepatitis B virus (HBV) and hepatitis C virus (HCV) . The seroprevalence of these infections varies among blood donors belonging to different parts of the world and determines the magnitude of Transfusion Transmitted Infection (TTI). Thus, a retrospective cross sectional observational study was conducted by reviewing the records from January 2015 to December 2017 in a Blood Bank of a tertiary care center to determine the seroprevalence and trends of HIV, HBV, HCV infections among the healthy blood donors in Eastern India. A total of 30622 people donated blood during the study period. Males formed the majority of the donor population accounting for 89.576 % (27430/30622) while females accounted for 10.423% (3192/30622) of donations. Majority of the donors were replacement donors (27253/ 30622= 89%) . The overall prevalence of transfusion-transmitted infection was 2.060 % (631/30622). The seropositivity for HBsAg, HCV, and HIV was 1.652%, 0.267%, and 0.140% respectively. Amongst all the seropositive sera for TTI, the seroprevalence of HBV infection was highest (80 %) and the seroprevalence of HCV & HIV infection was 13 % & 7 % respectively. The present study clearly documents the higher seroprevalence of HBV and HIV but lower prevalence of HCV infection in this part of eastern India in comparison to the national average. It also indicates lower participation of voluntary donors and female donors. Promoting the culture of voluntary donors, recruitment of female blood donors, vaccination of susceptible population against HBV infection, confirmatory test for seropositive sera by molecular methods, counselling the seropositive donors about the infection and advising them to take treatment at the designated centers are recommended.
Authors and Affiliations
Dr. Vidyut Prakash
Keywords
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