Serum 25(Oh) Vitamin D Inadequacy in Hypertensives and Its Influence on Lipidprofile
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 4
Abstract
Introduction:Highprevalence of vitamin D insufficiency is a particularly important public health. Hypovitaminosis D is associated with atherosclerosis, obesity, Insulin resistance, diabetes mellitus, hypertension, myocardial infarction, and stroke.Material & Methods: A total of 100 patients participated in the study in the age range of 15-85 years. Out of 100 patients, 50 patients had normal vitamin D levels whereas 50 patients had reduced levels of vitamin D. In both the test group and control group, the serum total cholesterol levels and triglycerides levels were compared.Results: The mean ± S.D of vitamin D in test group is15.89 ± 5.72 compared to the mean ± S.D in control group is 21.39 ± 4.77. The decreased vitamin D in test group is highly significant (P <0.001). Lipid parameters such as Triglycerides, LDL and VLDL were significantly higher in test group. Correlation between vitamin D and other parameters found that systolic BP, Diastolic BP, Triglycerides and VLDL had negative correlation with vitamin D levels. Whereas total cholesterol, HDL, LDL had positive correlation with statistically significance. Conclusions: In our study serum 25(OH) VITAMIN D levels aresignificantly decreased in patients with hypertension and its stronglycorrelate with lipid parameters.
Authors and Affiliations
Dr Mude Sarala, Dr Vijaya Kumari, Dr Ch. Venkata Ramana
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