SERUM CALCIUM IN PRIMARY POSTPARTUM HAEMORRHAGE
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 10
Abstract
Background: Postpartum haemorrhage may cause maternal mortality. Uterine atony is a major cause of primary post-partum haemorrhage (PPH). Calcium plays a role in uterine contraction and may contribute to the causation of uterine atony. Objective: To determine the serum calcium levels in parturient women and its relationship to primary PPH. Subject and Method: A cohort study of 140 consecutive parturient women at Nnamdi Azikiwe University Teaching Hospital, Nigeria, involving intrapertum estimation of serum calcium levels and relating it to primary PPH. Data analysis was done using SPSS version 21.0. Comparison of variables employed student’s t-test, with p-values of <0.05 at 95% confidence interval considered to be statistically significant. Results: of the 140 parturient, 97 (69.3%) had Spontaneous Vertex Delivery (SVD); 25 (17.9%), assisted delivery, and 18 (12.9%), caesarean section. Sixteen (11.4%) women (all with SVD) had primary PPH, 10 (62.5%) of which were due to uterine atony. The mean serum ionized calcium level of participants without primary PPH was higher (1.11±0.25 mmol/L) than that of participants who had primary PPH from uterine atony (1.0±0.35 mmol/L), (P = 0.037). Conclusion: This study shows that hypocalcaemia occurred in parturient women with primary PPH from uterine atony. Suggesting the role of adequate calcium in preventing obstetrics haemorrhage. The relationship between serum calcium and primary PPH could be explored in the development of predictive, preventive and therapeutic strategies for primary PPH and ultimate reduction of maternal morbidity and mortality from PPH.
Authors and Affiliations
Prof. Adinma J. I. B.
Keywords
Related Articles
- EP ID EP674336
- DOI -
- Views 183
- Downloads 0
EFFECTS OF STRONTIUM CHLORIDE HEXAHYDRATE IN CAENORHABDITIS ELEGANS INDIVIDUALS AS A MODEL FOR SKIN AGING
Backround: Collagen destruction is related to the presence of matrix metalloproteinase (MMP) that are released by epidermal keratinocytes and dermal fibroblasts and the MMP-1 expression stimulated by ultraviolet radiatio...
DOES PUMPKIN AFFECT GLYCEMIC CONTROL IN DIABETIC PATIENT. CASE REPORT AND LITERATURE REVIEW
Pumpkin was reported to have hypoglycemic effect. It has been used in asia as traditional treatment for diabetes mellitus. Here we report 12 year old Saudi who is diagnosed as diabetes mellitus type 1. The pumpkin was fe...
FORMULATION AND EVALUATION OF POLYHERBAL TRANSDERMAL GEL FOR ANTI-FUNGAL ACTIVITY
Conventional drug delivery system has many problems so bulk of research has now shifted from synthetic drugs to herbal drugs. This is possible because of the vast variety of bioactive molecules in the plants and their hi...
EFFECT OF SHRIMP SHELL EXTRACT NANOPARTICLES ON ORAL SQUAMOUS CELL CARCINOMA CELL LINE: IN VITRO STUDY
To develop a shrimp shell extract based nanoparticles formulation and assess its effect on the viability and carcinogenic potential of human oral squamous cell carcinoma cell line Hep-2 in vitro. Nanoparticles of chitosa...
COMMON CAUSES OF RISKY PREGNANCY AMONG PREGNANT WOMEN IN IRAQ
Introduction: Pregnancy factors are those that affect women's pregnancy and pregnancy requirements and its important because their consequences have a higher likelihood of complications or health problems during pregnanc...