Serum Sodium Levels and Probability of Recurrent Febrile Convulsions
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 2
Abstract
Introduction: Febrile seizures are seizures that occur between the age of 6 and 60 months with a temperature of 38°C or higher, that are not the result of the central nervous system infection or any metabolic imbalance, and that occur in the absence of a history of prior afebrile seizures. The mechanism of seizure activity is altered in hyponatremia, due to deficiency of sodium ion, more calcium ion influx, and generation of repetitive action potential which will cause repetitive seizure initiation. Aim: To estimate the serum sodium levels in children with febrile convulsions and analyze the probability of recurrent febrile convulsions. Materials and Methods: A prospective study which enrolled 190 children admitted with febrile seizures at Sivagangai Medical College Hospital. They were divided into five groups. Serum sodium levels were estimated. The probability of recurrent febrile convulsions and serum sodium was analyzed. The results obtained were statistically analyzed using Bartlett’s test. Results: A total of 53 of 190 children (29%) with febrile convulsion developed repeat convulsion. The mean sodium level in the group with repeat convulsion was 132.26 mmol/l which was significantly lower than the mean in the group without repeat convulsions. The increase in the probability of a repeat convulsion when the serum sodium level decreases are significant (P = 0.0025 [<0.05]). Conclusion: When the serum sodium level decreases, the probability of recurrent febrile convulsion increases. This knowledge may be of practical value in deciding whether to admit the child or allow it to return home and in advising parents or caregivers of the risk of a repeat convulsion.
Authors and Affiliations
M Kulandaivel
Keywords
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